AC T32110
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ID T32110
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DT 04.02.2002 (created); cch.
DT 25.05.2015 (updated); sup.
CO Copyright (C), QIAGEN.
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FA SIRT1
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SY silent information regulator type 1; SIR2alpha; sirtuin type 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006716 Sirt1.
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IN T02984 beta-catenin; mouse, Mus musculus.
IN T00122 c-Fos; mouse, Mus musculus.
IN T00131 c-Jun; mouse, Mus musculus.
IN T05866 Clock:BMAL1; mouse, Mus musculus.
IN T05868 Clock; mouse, Mus musculus.
IN T19634 HES 7; Mammalia.
IN T00422 IRF-1; mouse, Mus musculus.
IN T09576 LEF-1; mouse, Mus musculus.
IN T01806 p53; mouse, Mus musculus.
IN T10645 STAT5; mouse, Mus musculus.
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BS R67908.
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DR TRANSPATH: MO000023372.
DR UniProtKB: Q923E4;
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RN [1]; RE0020825.
RX PUBMED: 11672522.
RA Luo J., Nikolaev A. Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W.
RT Negative control of p53 by Sir2alpha promotes cell survival under stress
RL Cell 107:137-148 (2001).
RN [2]; RE0064434.
RX PUBMED: 18193082.
RA Binda O., Nassif C., Branton P. E.
RT SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.
RL Oncogene 27:3384-3392 (2008).
RN [3]; RE0065683.
RX PUBMED: 20016601.
RA Chen D., Pacal M., Wenzel P., Knoepfler P. S., Leone G., Bremner R.
RT Division and apoptosis of E2f-deficient retinal progenitors.
RL Nature 462:925-929 (2009).
RN [4]; RE0066089.
RX PUBMED: 20042607.
RA Zhang R., Chen H. Z., Liu J. J., Jia Y. Y., Zhang Z. Q., Yang R. F., Zhang Y., Xu J., Wei Y. S., Liu D. P., Liang C. C.
RT SIRT1 Suppresses Activator Protein-1 Transcriptional Activity and Cyclooxygenase-2 Expression in Macrophages.
RL J. Biol. Chem. 285:7097-7110 (2010).
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