AC T00795
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ID T00795
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DT 16.11.1992 (created); ewi.
DT 24.01.2008 (updated); smt.
CO Copyright (C), QIAGEN.
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FA TBP
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SY SPT15; TATA-binding protein; TBP; TFIID; TFIIDtau; yBTF1.
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OS fission yeast, Schizosaccharomyces pombe
OC Eukaryota; Fungi; Ascomycota; Archiascomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
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CL C0082; TATA; F4.6.1.0.1.
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SZ 231 AA; 25.4 kDa (gene) (calc.).
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SQ MDFALPTTASQASAFMNNSSLTFPVLPNANNEATNETADSGDAEVSKNEGVSGIVPTLQN
SQ IVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKSTALIFASGKMVVLGGKSE
SQ DDSKLASRKYARIIQKLGFNAKFTDFKIQNIVGSCDVKFPIRLEGLAYSHGTFSSYEPEL
SQ FPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAFEAIYPVLSEFRKH
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SC Swiss-Prot#P17871
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FT 53 138 PF00352; Transcription factor TFIID (or TATA-binding.
FT 143 229 PF00352; Transcription factor TFIID (or TATA-binding.
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SF 93% sequence identity with S. cerevisiae TBP within the conserved core region [2];
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FF although being highly conserved, the core region provides species-specific basic functions resulting in normal cell growth [3];
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IN T00068 Brf1p; yeast, Saccharomyces cerevisiae.
IN T00182 DBF4; human, Homo sapiens.
IN T00530 NC1; human, Homo sapiens.
IN T02068 PU.1-isoform1; human, Homo sapiens.
IN T00702 PU.1; mouse, Mus musculus.
IN T00759 Sp1; human, Homo sapiens.
IN T00787 TAF-L; human, Homo sapiens.
IN T00894 Vmw65; HSV-1, herpes simplex virus type 1.
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MX M00713 F$TBP_Q6.
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BS R02688.
BS R00367.
BS R00998.
BS R23018.
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DR EMBL: X53415; SPTFIID.
DR UniProtKB: P17871; TF2D_SCHPO.
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RN [1]; RE0000713.
RX PUBMED: 2210373.
RA Hoffmann A., Horikoshi M., Wang C. K., Schroeder St., Weil P. A., Roeder R. G.
RT Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID
RL Genes Dev. 4:1141-1148 (1990).
RN [2]; RE0005574.
RX PUBMED: 2197558.
RA Fikes J. D., Becker D. M., Winston F., Guarente L.
RT Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae
RL Nature 346:291-294 (1990).
RN [3]; RE0005576.
RX PUBMED: 2015627.
RA Gill G., Tjian R.
RT A highly conserved domain of TFIID displays species specificity in vivo
RL Cell 65:333-340 (1991).
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