AC T01154
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ID T01154
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DT 26.04.1994 (created); ewi.
DT 07.01.2015 (updated); sup.
CO Copyright (C), QIAGEN.
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FA c-Rel
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SY c-Rel; HIVEN86A (human); p68; p82(hc-rel).
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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CL C0020; Rel.
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SF trans-activation domains contact TBP directly [9];
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CP high levels: apoptotic or autophagocytotic cells; low: ubiquitous [8].
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FF potent activator [7] [10];
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IN T01937 IkappaB-alpha; chick, Gallus gallus.
IN T00416 IkappaB-beta; chick, Gallus gallus.
IN T00971 IkappaB-beta; mouse, Mus musculus.
IN T00593 NF-kappaB1-p50; human, Homo sapiens.
IN T01925 NF-kappaB1; human, Homo sapiens.
IN T00897 v-Rel; REV-T, reticuloendotheliosis virus (strain T).
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MX M00053 V$CREL_01.
MX M03545 V$CREL_Q6.
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BS R02668.
BS R04704.
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DR TRANSPATH: MO000019370.
DR UniProtKB: P16236; REL_CHICK.
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RN [1]; RE0002464.
RX PUBMED: 1848011.
RA Kabrun N., Hodgson J. W., Doemer M., Mak G., Franza jr B. R., Enrietto P. J.
RT Interaction of the v-rel protein with an NF-kappaB DNA binding site
RL Proc. Natl. Acad. Sci. USA 88:1783-1787 (1991).
RN [2]; RE0004479.
RX PUBMED: 2555689.
RA Hannink M., Temin H. M.
RT Transactivation of gene expression by nuclear and cytoplasmic rel proteins
RL Mol. Cell. Biol. 9:4323-4336 (1989).
RN [3]; RE0004488.
RX PUBMED: 2167440.
RA Kabrun N., Bumstead N., Hayman M. J., Enrietto P. J.
RT Characterization of a novel promoter insertion in the c-rel locus
RL Mol. Cell. Biol. 10:4788-4794 (1990).
RN [4]; RE0004566.
RX PUBMED: 2179815.
RA Capobianco A. J., Simmons D. L., Gilmore T. D.
RT Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts
RL Oncogene 5:257-265 (1990).
RN [5]; RE0004567.
RX PUBMED: 1766669.
RA Capobianco A. J., Gilmore T. D.
RT Repression of the chicken c-rel promoter by vRel in chicken embryo fibroblasts is not mediated through a consensus NF-kB binding site
RL Oncogene 6:2203-2210 (1991).
RN [6]; RE0004568.
RX PUBMED: 2284104.
RA Hannink M., Temin H. M.
RT Structure and auto regulation of the c-rel promoter
RL Oncogene 5:1843-1850 (1990).
RN [7]; RE0004574.
RX PUBMED: 1903456.
RA Richardson P. M., Gilmore T. D.
RT vRel is an inactive member of the Rel family of transcriptional activating proteins
RL J. Virol. 65:3122-3130 (1991).
RN [8]; RE0004578.
RX PUBMED: 8252626.
RA Abbadie C., Kabrun N., Bouali F., Smardova J., StJhelin D., Vandenbunder B., Enrietto P. J.
RT High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro
RL Cell 75:899-912 (1993).
RN [9]; RE0004579.
RX PUBMED: 8413269.
RA Xu X., Prorock C., Ishikawa H., Maldonado E., Ito Y., GJlinas C.
RT Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB
RL Mol. Cell. Biol. 13:6733-6741 (1993).
RN [10]; RE0004685.
RX PUBMED: 2111443.
RA Kamens J., Richardson P., Mosialos G., Brent R., Gilmore T.
RT Oncogenic transformation by vRel requires an amino-terminal activation domain
RL Mol. Cell. Biol. 10:2840-2847 (1990).
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