TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01154 XX ID T01154 XX DT 26.04.1994 (created); ewi. DT 07.01.2015 (updated); sup. CO Copyright (C), QIAGEN. XX FA c-Rel XX SY c-Rel; HIVEN86A (human); p68; p82(hc-rel). XX OS chick, Gallus gallus OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae XX CL C0020; Rel. XX SF trans-activation domains contact TBP directly [9]; XX CP high levels: apoptotic or autophagocytotic cells; low: ubiquitous [8]. XX FF potent activator [7] [10]; XX IN T01937 IkappaB-alpha; chick, Gallus gallus. IN T00416 IkappaB-beta; chick, Gallus gallus. IN T00971 IkappaB-beta; mouse, Mus musculus. IN T00593 NF-kappaB1-p50; human, Homo sapiens. IN T01925 NF-kappaB1; human, Homo sapiens. IN T00897 v-Rel; REV-T, reticuloendotheliosis virus (strain T). XX MX M00053 V$CREL_01. MX M03545 V$CREL_Q6. XX BS R02668. BS R04704. XX DR TRANSPATH: MO000019370. DR UniProtKB: P16236; REL_CHICK. XX RN [1]; RE0002464. RX PUBMED: 1848011. RA Kabrun N., Hodgson J. W., Doemer M., Mak G., Franza jr B. R., Enrietto P. J. RT Interaction of the v-rel protein with an NF-kappaB DNA binding site RL Proc. Natl. Acad. Sci. USA 88:1783-1787 (1991). RN [2]; RE0004479. RX PUBMED: 2555689. RA Hannink M., Temin H. M. RT Transactivation of gene expression by nuclear and cytoplasmic rel proteins RL Mol. Cell. Biol. 9:4323-4336 (1989). RN [3]; RE0004488. RX PUBMED: 2167440. RA Kabrun N., Bumstead N., Hayman M. J., Enrietto P. J. RT Characterization of a novel promoter insertion in the c-rel locus RL Mol. Cell. Biol. 10:4788-4794 (1990). RN [4]; RE0004566. RX PUBMED: 2179815. RA Capobianco A. J., Simmons D. L., Gilmore T. D. RT Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts RL Oncogene 5:257-265 (1990). RN [5]; RE0004567. RX PUBMED: 1766669. RA Capobianco A. J., Gilmore T. D. RT Repression of the chicken c-rel promoter by vRel in chicken embryo fibroblasts is not mediated through a consensus NF-kB binding site RL Oncogene 6:2203-2210 (1991). RN [6]; RE0004568. RX PUBMED: 2284104. RA Hannink M., Temin H. M. RT Structure and auto regulation of the c-rel promoter RL Oncogene 5:1843-1850 (1990). RN [7]; RE0004574. RX PUBMED: 1903456. RA Richardson P. M., Gilmore T. D. RT vRel is an inactive member of the Rel family of transcriptional activating proteins RL J. Virol. 65:3122-3130 (1991). RN [8]; RE0004578. RX PUBMED: 8252626. RA Abbadie C., Kabrun N., Bouali F., Smardova J., StJhelin D., Vandenbunder B., Enrietto P. J. RT High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro RL Cell 75:899-912 (1993). RN [9]; RE0004579. RX PUBMED: 8413269. RA Xu X., Prorock C., Ishikawa H., Maldonado E., Ito Y., GJlinas C. RT Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB RL Mol. Cell. Biol. 13:6733-6741 (1993). RN [10]; RE0004685. RX PUBMED: 2111443. RA Kamens J., Richardson P., Mosialos G., Brent R., Gilmore T. RT Oncogenic transformation by vRel requires an amino-terminal activation domain RL Mol. Cell. Biol. 10:2840-2847 (1990). XX //