AC T04141
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ID T04141
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DT 29.12.2000 (created); rio.
CO Copyright (C), QIAGEN.
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FA Chx10-1
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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HO ceh-10 T02980 (C. elegans).
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CL C0006; homeo.
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SZ 350 AA; 37.3 kDa (cDNA) (calc.).
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SQ MPGRADPSGGRAAVPVPLPVAVAAAPSPASVRSALPERSARPGGAGLRAKGFAITDLLGL
SQ EAELQPPPGAAPGPAGGYEGGGALGLGLGLLCGLAGPGAPCLLPAPLPLLPARGPRPGPP
SQ GPPPAARRHKESASDEDSLSGDASELKMPASQIKRKKRRHRTVFTAHQLEELEKAFNEAH
SQ YPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIP
SQ LPESIINSAKSGLVGSCAPWLLGMHKKSMEVSRKAESQEKPADGWQAEQDGEELQGKQAS
SQ SQRSSEKLGPAKDPEDTAIDLSRTAKQEKRSVLRQCVNGDPTTEQKDRDH
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SC translated from EMBL #AF178670
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FT 1 291 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 155 215 
PS50071; HOMEOBOX_2.
FT 157 213 
PS50552; PAX.
FT 157 219 
SM00389; HOX_1.
FT 158 214 
PF00046; Homeobox domain.
FT 218 270 
CVC domain [1].
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SF contains CVC domain which is a conserved region in Chx10/Vsx-1 T04139 T02970 T04143 T04144 and ceh-10 T02980 [1] [2];
SF two orthologs in chicken: Chx10 T04142 and Chx10-1 [1];
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CP (stage 12:) neural retina of invaginating optic vesicles, ventral spinal cord, (stage 14:) retinoblasts, spinal cord, (stage 15-23:) nasal and temporal domains of retina, spinal cord, (stage 29-adult:) bipolar cells of inner nuclear layer [1].
CN (stage 12:) pigment epithelium, lens, (stage 35-adult:) inner half of nuclear layer, ganglion cells [1].
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DR TRANSPATH: MO000028043.
DR EMBL: AF178670;
DR UniProtKB: Q9IAL2;
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RN [1]; RE0015514.
RX PUBMED: 10640715.
RA Amy Chen C. M., Cepko C. L.
RT Expression of Chx10 and Chx10-1 in the developing chicken retina
RL Mech. Dev. 90:293-297 (2000).
RN [2]; RE0015515.
RX PUBMED: 7789259.
RA Svendsen P. C., McGhee J. D.
RT The C. elegans neuronally expressed homeobox gene ceh-10 is closely related to genes expressed in the vertebrate eye
RL Development 121:1253-1262 (1995).
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