AC T09402
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ID T09402
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DT 10.03.2005 (created); nvo.
DT 13.02.2015 (updated); smt.
CO Copyright (C), QIAGEN.
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FA MEF-2C
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SY myocyte-specific enhancer factor 2C.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T02404 Dermo-1; mouse, Mus musculus.
IN T14713 FOXK1; mouse, Mus musculus.
IN T21754 FoxK1; Mammalia.
IN T08522 HDAC4-isoform1; human, Homo sapiens.
IN T10027 MyoD; Mammalia.
IN T23091 p300; Mammalia.
IN T28267 PGC-1; Mammalia.
IN T09956 PPARalpha; Mammalia.
IN T24830 Smad2; Mammalia.
IN T17039 TEF-1; Mammalia.
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MX M02025 V$MEF2C_Q4.
MX M00941 V$MEF2_Q6_01.
MX M07424 V$MEF2_Q6_03.
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BS R66252.
BS R61893.
BS R64134.
BS R64137.
BS R64140.
BS R64141.
BS R64142.
BS R42396.
BS R33495.
BS R09465.
BS R24919.
BS R24920.
BS R33591.
BS R31580.
BS R19560.
BS R65901.
BS R65903.
BS R65904.
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DR TRANSPATH: MO000046322.
DR TRANSCOMPEL: C00488.
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RN [1]; RE0015066.
RX PUBMED: 9753748.
RA Yang C.C., Ornatsky O.I., McDermott J.C., Cruz T.F., Prody C.A.
RT Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1
RL Nucleic Acids Res. 26:4771-4777 (1998).
RN [2]; RE0015233.
RX PUBMED: 9001254.
RA Sartorelli V., Huang J., Hamamori Y., Kedes L.
RT Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C
RL Mol. Cell. Biol. 17:1010-1026 (1997).
RN [3]; RE0015238.
RX PUBMED: 10330143.
RA Yang S. H., Galanis A., Sharrocks A. D.
RT Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors
RL Mol. Cell. Biol. 19:4028-4038 (1999).
RN [4]; RE0027429.
RX PUBMED: 11160896.
RA Quinn Z. A., Yang C. C., Wrana J. L., McDermott J. C.
RT Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.
RL Nucleic Acids Res. 29:732-742 (2001).
RN [5]; RE0027858.
RX PUBMED: 11274399.
RA Michael L. F., Wu Z., Cheatham R. B., Puigserver P., Adelmant G., Lehman J. J., Kelly D. P., Spiegelman B. M.
RT Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.
RL Proc. Natl. Acad. Sci. USA 98:3820-5 (2001).
RN [6]; RE0031980.
RX PUBMED: 12659851.
RA Huang J., Tu Z., Lee F. S.
RT Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity.
RL Biochem. Biophys. Res. Commun. 303:532-40 (2003).
RN [7]; RE0033883.
RX PUBMED: 10781804.
RA Skerjanc I. S., Wilton S.
RT Myocyte enhancer factor 2C upregulates MASH-1 expression and induces neurogenesis in P19 cells.
RL FEBS Lett. 472:53-6 (2000).
RN [8]; RE0041339.
RX PUBMED: 12061776.
RA Maeda T., Gupta M. P., Stewart A. F.
RT TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters
RL Biochem. Biophys. Res. Commun. 294:791-7 (2002).
RN [9]; RE0041786.
RX PUBMED: 10849446.
RA Kato Y., Zhao M., Morikawa A., Sugiyama T., Chakravortty D., Koide N., Yoshida T., Tapping R. I., Yang Y., Yokochi T., Lee J. D.
RT Big mitogen-activated kinase regulates multiple members of the MEF2 protein family
RL J. Biol. Chem. 275:18534-40 (2000).
RN [10]; RE0042150.
RX PUBMED: 15073151.
RA Chen H., Shi S., Acosta L., Li W., Lu J., Bao S., Chen Z., Yang Z., Schneider M. D., Chien K. R., Conway S. J., Yoder M. C., Haneline L. S., Franco D., Shou W.
RT BMP10 is essential for maintaining cardiac growth during murine cardiogenesis
RL Development 131:2219-31 (2004).
RN [11]; RE0043022.
RX PUBMED: 11792813.
RA Borghi S., Molinari S., Razzini G., Parise F., Battini R., Ferrari S.
RT The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4
RL J. Cell Sci. 114:4477-83 (2001).
RN [12]; RE0043445.
RX PUBMED: 9748293.
RA Rao S., Karray S., Gackstetter E. R., Koshland M. E.
RT Myocyte enhancer factor-related B-MEF2 is developmentally expressed in B cells and regulates the immunoglobulin J chain promoter
RL J. Biol. Chem. 273:26123-9 (1998).
RN [13]; RE0043447.
RX PUBMED: 11713257.
RA Chen S. L., Loffler K. A., Chen D., Stallcup M. R., Muscat G. E.
RT The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2
RL J. Biol. Chem. 277:4324-33 (2002).
RN [14]; RE0044082.
RX PUBMED: 15356291.
RA Baldan A., Relat J., Marrero P. F., Haro D.
RT Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation
RL Nucleic Acids Res. 32:4742-9 (2004).
RN [15]; RE0048109.
RX PUBMED: 10817756.
RA Chen S. L., Dowhan D. H., Hosking B. M., Muscat G. E.
RT The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation.
RL Genes Dev. 14:1209-1228 (2000).
RN [16]; RE0048147.
RX PUBMED: 11279209.
RA Dressel U., Bailey P. J., Wang S. C., Downes M., Evans R. M., Muscat G. E.
RT A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.
RL J. Biol. Chem. 276:17007-17013 (2001).
RN [17]; RE0048453.
RX PUBMED: 12032081.
RA Kirsh O., Seeler J. S., Pichler A., Gast A., Muller S., Miska E., Mathieu M., Harel-Bellan A., Kouzarides T., Melchior F., Dejean A.
RT The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.
RL EMBO J. 21:2682-2691 (2002).
RN [18]; RE0051897.
RX PUBMED: 16626623.
RA Ranganathan A., Pearson G. W., Chrestensen C. A., Sturgill T. W., Cobb M. H.
RT The MAP kinase ERK5 binds to and phosphorylates p90 RSK.
RL Arch. Biochem. Biophys. 449:8-16 (2006).
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