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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T14258 XX ID T14258 XX DT 05.09.2006 (created); rad. DT 12.02.2009 (updated); smt. CO Copyright (C), QIAGEN. XX FA Nkx3-2 XX SY Homeobox protein NKX3.2; NK class homeodomain transcription factor NKX3.2; Nkx-3.2. XX OS chick, Gallus gallus OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae XX GE G037271 NKX3-2. XX SZ 276 AA; 29.2 kDa (cDNA) (calc.). XX SQ MAVRGGGGGGGTALTPFSIQAILNKKEERARGWRLCAARAEAPPPPAPRPPPAWDSDSAL SQ SEEPESERRSEEESAGGSARPPEAAGRGAAGGGGAALGGGGGAGPGPGRSAQRQRSVGRR SQ LRSRPGRGGGGGGGRLLAAEEEAAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPER SQ ADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLAAAPAAKKVAVKVLVRDDQRQYQPG SQ EVLRPPSLLALQPSYYYPYYCLPGWALSCAAAAGTQ XX SC translated from EMBL:AF138905 XX FT 148 208 PS50071; HOMEOBOX_2. FT 150 212 SM00389; HOX_1. FT 151 207 PF00046; Homeobox. XX FF N200Q missense mutation of the homeodomain alters the DNA binding activity of this molecule, keeping the repression activity intact. [2]; FF The DNA binding activity promotes chondrocyte differentiation program in somitic tissue. [2]; XX IN T21852 HDAC1; Mammalia. IN T09175 Smad1-isoform1; human, Homo sapiens. IN T10783 Smad1; Mammalia. IN T24830 Smad2; Mammalia. IN T13998 Smad4; Mammalia. XX MX M01181 V$NKX32_01. MX M01482 V$NKX32_02. XX BS R23778. BS R23779. BS R23780. BS R23781. BS R23782. BS R23784. BS R23785. BS R23786. BS R23787. BS R23788. BS R23789. BS R23790. BS R23791. BS R23792. BS R23793. BS R23794. BS R23795. BS R23796. BS R23797. BS R23798. BS R23799. BS R23800. BS R23801. BS R23802. BS R23803. BS R23804. BS R23805. BS R23806. BS R26725. XX DR TRANSPATH: MO000086336. DR TRANSCOMPEL: C00508. DR EMBL: AF138905; DR UniProtKB: Q9PRJ1; Q9PRJ1. XX RN [1]; RE0032276. RX PUBMED: 14612411. RA Kim D. W., Lassar A. B. RT Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2. RL Mol. Cell. Biol. 23:8704-17 (2003). RN [2]; RE0052071. RX PUBMED: 12746429. RA Kim D. W., Kempf H., Chen R. E., Lassar A. B. RT Characterization of Nkx3.2 DNA binding specificity and its requirement for somitic chondrogenesis. RL J. Biol. Chem. 278:27532-27539 (2003). XX //