TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T21600 XX ID T21600 XX DT 18.04.2002 (created); cch. DT 07.01.2015 (updated); msr. CO Copyright (C), QIAGEN. XX FA nucleolin XX SY C23; NCL; nucleolin; protein C23. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G006456 NCL; HGNC: NCL. XX CP erythroleukemia cell line K562 [1]. XX FF exhibits somewhat lower binding affinity to double-stranded MARs than SATB1 [1]; FF recognizes specifically the unpairing region of MARs [1]; FF binds through minor groove of the double-stranded MAR [1]; FF binds the single-stranded T-rich strand more efficiently [1]; FF not affected by apoptosis in hematopoietic cell line [3]; XX IN T02337 ALL1; human, Homo sapiens. IN T15204 brca1; Mammalia. IN T00045 COUP-TF2; human, Homo sapiens. IN T08494 Erg; human, Homo sapiens. IN T02186 MO15; human, Homo sapiens. IN T15720 NF90; human, Homo sapiens. IN T27304 PHF5A; human, Homo sapiens. IN T05443 RFXAP; human, Homo sapiens. IN T08660 YY1; human, Homo sapiens. XX BS R56756. BS R60711. BS R64854. BS R34319. XX DR TRANSPATH: MO000031061. DR SMARTDB: SB000020. DR UniProtKB: P19338; XX RN [1]; RE0007007. RX PUBMED: 7799955. RA Dickinson L. A., Kohwi-Shigematsu T. RT Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential RL Mol. Cell. Biol. 15:456-465 (1995). RN [2]; RE0007008. RX PUBMED: 2737305. RA Srivastava M., Fleming P. J., Pollard H. B., Burns A. L. RT Cloning and sequencing of the human nucleolin cDNA RL FEBS Lett. 250:99-105 (1989). RN [3]; RE0017467. RX PUBMED: 10025665. RA Martelli A. M., Bortul R., Fackelmayer F. O., Tazzari P. L., Bareggi R., Narducci P., Zweyer M. RT Biochemical and morphological characterization of the nuclear matrix from apoptotic HL-60 cells RL J. Cell. Biochem. 72:35-46 (1999). RN [4]; RE0035741. RX PUBMED: 10607589. RA Dumler I., Stepanova V., Jerke U., Mayboroda O. A., Vogel F., Bouvet P., Tkachuk V., Haller H., Gulba D. C. RT Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin. RL Curr. Biol. 9:1468-1476 (1999). RN [5]; RE0035751. RX PUBMED: 15051732. RA Sakaguchi M., Miyazaki M., Sonegawa H., Kashiwagi M., Ohba M., Kuroki T., Namba M., Huh N. H. RT PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11. RL J. Cell Biol. 164:979-984 (2004). RN [6]; RE0036155. RX PUBMED: 11736641. RA Harms G., Kraft R., Grelle G., Volz B., Dernedde J., Tauber R. RT Identification of nucleolin as a new L-selectin ligand. RL Biochem. J. 360:531-538 (2001). RN [7]; RE0036529. RX PUBMED: 15121898. RA Villace P., Marion R. M., Ortin J. RT The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs RL Nucleic Acids Res. 32:2411-20 (2004). RN [8]; RE0048218. RX PUBMED: 16226712. RA Niture S. K., Doneanu C. E., Velu C. S., Bailey N. I., Srivenugopal K. S. RT Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry. RL Biochem. Biophys. Res. Commun. 337:1176-1184 (2005). RN [9]; RE0048840. RX PUBMED: 15684379. RA Korgaonkar C., Hagen J., Tompkins V., Frazier A. A., Allamargot C., Quelle F. W., Quelle D. E. RT Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function. RL Mol. Cell. Biol. 25:1258-1271 (2005). RN [10]; RE0048947. RX PUBMED: 16582619. RA Tompkins V., Hagen J., Zediak V. P., Quelle D. E. RT Identification of novel ARF binding proteins by two-hybrid screening. RL Cell Cycle 5:641-646 (2006). RN [11]; RE0050746. RX PUBMED: 17643122. RA Kim H., Huang J., Chen J. RT CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. RL Nat. Struct. Mol. Biol. 14:710-715 (2007). RN [12]; RE0053112. RX PUBMED: 18292223. RA Padilla P. I., Uhart M., Pacheco-Rodriguez G., Peculis B. A., Moss J., Vaughan M. RT Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin. RL Proc. Natl. Acad. Sci. USA 105:3357-3361 (2008). RN [13]; RE0054024. RX PUBMED: 18523588. RA Di Segni A., Farin K., Pinkas-Kramarski R. RT Identification of nucleolin as new ErbB receptors- interacting protein. RL PLoS ONE 3:e2310 (2008). RN [14]; RE0067874. RX PUBMED: 11115514. RA Gil D., Gutierrez D., Alarcon B. RT Intracellular redistribution of nucleolin upon interaction with the CD3epsilon chain of the T cell receptor complex. RL J. Biol. Chem. 276:11174-11179 (2001). RN [15]; RE0074469. RX PUBMED: 22693611. RA Litchfield L. M., Riggs K. A., Hockenberry A. M., Oliver L. D., Barnhart K. G., Cai J., Pierce WM J. r., Ivanova M. M., Bates P. J., Appana S. N., Datta S., Kulesza P., McBryan J., Young L. S., Klinge C. M. RT Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor beta transcription in breast cancer cells. RL PLoS ONE 7:e38278 (2012). XX //