AC T25624
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ID T25624
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DT 03.11.2005 (created); jma.
DT 16.10.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA p/CAF
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SY CAF; K(lysine) acetyltransferase 2B; KAT2B; P/CAF; p300/CBP-associated factor; PCAF.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003808 KAT2B; HGNC: KAT2B.
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IN T06570 Dnmt1; human, Homo sapiens.
IN T15605 E2A; human, Homo sapiens.
IN T08230 ER81; human, Homo sapiens.
IN T05220 Evi-1; human, Homo sapiens.
IN T02066 Fli-1; human, Homo sapiens.
IN T00330 GLI; human, Homo sapiens.
IN T09015 HNF-1alpha; human, Homo sapiens.
IN T06376 ING1; human, Homo sapiens.
IN T04909 MOP4; human, Homo sapiens.
IN T23827 SATB2; human, Homo sapiens.
IN T29717 SIRT1; human, Homo sapiens.
IN T08256 SRC-1A; human, Homo sapiens.
IN T00835 TMF; human, Homo sapiens.
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DR TRANSPATH: MO000056491.
DR UniProtKB: Q92831;
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RN [1]; RE0027648.
RX PUBMED: 10777539.
RA Soutoglou E., Papafotiou G., Katrakili N., Talianidis I.
RT Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins.
RL J. Biol. Chem. 275:12515-20 (2000).
RN [2]; RE0029643.
RX PUBMED: 12015309.
RA Vieyra D., Loewith R., Scott M., Bonnefin P., Boisvert F. M., Cheema P., Pastyryeva S., Meijer M., Johnston R. N., Bazett-Jones D. P., McMahon S., Cole M. D., Young D., Riabowol K.
RT Human ING1 proteins differentially regulate histone acetylation.
RL J. Biol. Chem. 277:29832-9 (2002).
RN [3]; RE0035553.
RX PUBMED: 14701848.
RA Qiu Y., Guo M., Huang S., Stein R.
RT Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression.
RL J. Biol. Chem. 279:9796-9802 (2004).
RN [4]; RE0047639.
RX PUBMED: 12068014.
RA Jin Y., Zeng S. X., Dai M. S., Yang X. J., Lu H.
RT MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation.
RL J. Biol. Chem. 277:30838-30843 (2002).
RN [5]; RE0048066.
RX PUBMED: 12887892.
RA Fulco M., Schiltz R. L., Iezzi S., King M. T., Zhao P., Kashiwaya Y., Hoffman E., Veech R. L., Sartorelli V.
RT Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.
RL Mol. Cell 12:51-62 (2003).
RN [6]; RE0048931.
RX PUBMED: 12435739.
RA Bradney C., Hjelmeland M., Komatsu Y., Yoshida M., Yao T. P., Zhuang Y.
RT Regulation of E2A activities by histone acetyltransferases in B lymphocyte development.
RL J. Biol. Chem. 278:2370-2376 (2003).
RN [7]; RE0049018.
RX PUBMED: 16024795.
RA Huang W. C., Chen C. C.
RT Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity.
RL Mol. Cell. Biol. 25:6592-6602 (2005).
RN [8]; RE0050138.
RX PUBMED: 17293853.
RA Linares L. K., Kiernan R., Triboulet R., Chable-Bessia C., Latreille D., Cuvier O., Lacroix M., Le Cam L., Coux O., Benkirane M.
RT Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2.
RL Nat. Cell Biol. 9:331-338 (2007).
RN [9]; RE0054989.
RX PUBMED: 15604093.
RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M.
RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
RL Mol. Cell. Proteomics 4:205-213 (2005).
RN [10]; RE0067360.
RX PUBMED: 15647279.
RA Huang W., Zhao S., Ammanamanchi S., Brattain M., Venkatasubbarao K., Freeman J. W.
RT Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex.
RL J. Biol. Chem. 280:10047-10054 (2005).
RN [11]; RE0071919.
RX PUBMED: 19158279.
RA Asano Y., Trojanowska M.
RT Phosphorylation of Fli1 at threonine 312 by protein kinase C delta promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor beta.
RL Mol. Cell. Biol. 29:1882-1894 (2009).
RN [12]; RE0072504.
RX PUBMED: 21444723.
RA Pillai V. B., Sundaresan N. R., Samant S. A., Wolfgeher D., Trivedi C. M., Gupta M. P.
RT Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes.
RL Mol. Cell. Biol. 31:2349-2363 (2011).
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