AC T00043
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ID T00043
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DT 12.03.1993 (created); ewi.
DT 29.11.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Arg80p
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SY ARG80; ARG80p; ARGR1; ARGRI; YMR042W.
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OS yeast, Saccharomyces cerevisiae
OC Eukaryota; Fungi; Ascomycota; Hemiascomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
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GE G091144 ARG80.
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CL C0014; MADS; F4.4.3.0.1.
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SZ 177 AA; 19.5 kDa (gene) (calc.).
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SQ MTSNSDGSSTSPVEKPITGDVETNEPTKPIRRLSTPSPEQDQEGDFDEEDDDDKFSVSTS
SQ TPTPTITKTKDSSDTSTVTRRKQPIRYIENKTRRHVTFSKRRHGIMKKAYELSVLTGANI
SQ LLLILANSGLVYTFTTPKLEPVVREDEGKSLIRACINASDTPDATDTSPAQEQSPAN
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SC Swiss-Prot#P07249
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FT 78 137 SM00432; MADS.
FT 78 138 PS50066; MADS_BOX_2.
FT 86 136 PF00319; SRF-type transcription factor (DNA-binding a.
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SF does not interact with TCF (p62TCF) [1];
SF interacts with Mcm1p T00500and is stabilized by Arg82p T01259 [5];
SF DNA bending of the QPPAL binding site [6];
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FF controls arginine metabolism: repressor of arginine syntheses, induces Arg catabolism [2];
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IN T00044 Arg81p; yeast, Saccharomyces cerevisiae.
IN T01259 Arg82p; yeast, Saccharomyces cerevisiae.
IN T00500 Mcm1p; yeast, Saccharomyces cerevisiae.
IN T00765 SRF-L; mouse, Mus musculus.
IN T00761 SRF; chick, Gallus gallus.
IN T00762 SRF; cat, Felis silvestris catus.
IN T00763 SRF; clawed frog, Xenopus laevis.
IN T00764 SRF; human, Homo sapiens.
IN T00766 SRF; rat, Rattus norvegicus.
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MX M01673 F$ARGRI_01.
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BS R00466.
BS R03057.
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DR EMBL: X05327; SCARGI.
DR UniProtKB: P07249; ARG1_YEAST.
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RN [1]; RE0000532.
RX PUBMED: 1756729.
RA Mueller C. G. F., Nordheim A.
RT A protein domain conserved between yeast MCM1 and human SRF directs ternary complex formation
RL EMBO J. 10:4219-4229 (1991).
RN [2]; RE0001618.
RX PUBMED: 2005902.
RA Dubois E., Messenguy F.
RT In vitro studies of the binding of the ARGR proteins to the ARG5,6 promoter
RL Mol. Cell. Biol. 11:2162-2168 (1991).
RN [3]; RE0001688.
RX PUBMED: 8417320.
RA Sharrocks A. D., Gille H., Shaw P. E.
RT Identification of amino acids essential for DNA binding and dimerization in p67SRF: implications for a novel DNA-binding motif
RL Mol. Cell. Biol. 13:123-132 (1993).
RN [4]; RE0004116.
RX PUBMED: 3298999.
RA Dubois E., Bercy J., Messenguy F.
RT Characterization of two genes, ARGRI and ARGRIII required for specific regulation of arginine metabolism in yeast
RL Mol. Gen. Genet. 207:142-148 (1987).
RN [5]; RE0015874.
RX PUBMED: 10632874.
RA El Bakkoury M., Dubois E., Messenguy F.
RT Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability.
RL Mol. Microbiol. 35:15-31 (2000).
RN [6]; RE0022791.
RX PUBMED: 10064699.
RA West A. G., Sharrocks A. D.
RT MADS-box transcription factors adopt alternative mechanisms for bending DNA.
RL J. Mol. Biol. 286:1311-1323 (1999).
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