AC T00721
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ID T00721
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DT 14.12.1992 (created); ewi.
DT 12.03.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA NR1B2
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SY NR1B2; RAR-beta; retinoic acid receptor beta.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G000376 RARB; HGNC: RARB.
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CL C0002; CC (rec); 2.1.2.1.2.
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SF 3 N-terminally differing splice variants;
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CP SK-N-BE(2)C cells [11].
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FF negative regulation of AP-1 responsive genes;
FF activator of HOXA1 T01696 by binding to a 3' enhancer retinoic acid responsive element (RARE) [9];
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IN T01331 RXR-alpha; mouse, Mus musculus.
IN T01345 RXR-alpha; human, Homo sapiens.
IN T01359 RXR-alpha; clawed frog, Xenopus laevis.
IN T01334 RXR-beta; human, Homo sapiens.
IN T04807 RXR-gamma; human, Homo sapiens.
IN T04689 SMRT; human, Homo sapiens.
IN T04632 SRC-1; human, Homo sapiens.
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MX M00965 V$DR4_Q2.
MX M02111 V$NR1B2_Q6.
MX M07280 V$NR1NR2_Q3.
MX M08035 V$RARB_02.
MX M00963 V$T3R_Q6.
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BS R03933.
BS R01465.
BS R04508.
BS R04519.
BS R03017.
BS R00135.
BS R41982.
BS R41983.
BS R62967.
BS R01321.
BS R27355.
BS R03929.
BS R13314.
BS R13317.
BS R66743.
BS R27612.
BS R02856.
BS R04761.
BS R09141.
BS R03928.
BS R01063.
BS R04451.
BS R04634.
BS R02240.
BS R03932.
BS R03931.
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DR TRANSPATH: MO000019618.
DR UniProtKB: P10826; RRB2_HUMAN.
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RN [1]; RE0000265.
RX PUBMED: 1310259.
RA Leid M., Kastner P., Lyons R., Nakshatri H., Saunders M., Zacharewski T., Chen J.-Y., Staub A., Garnier J.-M., Mader S., Chambon P.
RT Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
RL Cell 68:377-395 (1992).
RN [2]; RE0000554.
RX PUBMED: 2176152.
RA Nicholson R. C., Mader S., Nagpal S., Leid M., Rochette-Egly C., Chambon P.
RT Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site
RL EMBO J. 9:4443-4454 (1990).
RN [3]; RE0001604.
RX PUBMED: 1996113.
RA Duester G., Shean M. L., McBride M. S., Stewart M. J.
RT Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis
RL Mol. Cell. Biol. 11:1638-1646 (1991).
RN [4]; RE0001916.
RX PUBMED: 1323763.
RA Zhang X.-K., Lehmann J., Hoffmann B., Dawson M. I., Cameron J., Graupner G., Hermann T., Tran P., Pfahl M.
RT Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid
RL Nature 358:587-591 (1992).
RN [5]; RE0001917.
RX PUBMED: 1310350.
RA Zhang X. K., Hoffmann B., Tran P. B.-V., Graupner G., Pfahl M.
RT Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
RL Nature 355:441-446 (1992).
RN [6]; RE0002399.
RX PUBMED: 2164682.
RA Sucov H. M., Murakami K. K., Evans R. M.
RT Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene
RL Proc. Natl. Acad. Sci. USA 87:5392-5396 (1990).
RN [7]; RE0002566.
RX PUBMED: 1648728.
RA Schuele R., Rangarajan P., Yang N., Kliewer S., Ransone L. J., Bolado J., Verma I. M., Evans R. M.
RT Retinoic acid is a negative regulator of AP-1-responsive genes
RL Proc. Natl. Acad. Sci. USA 88:6092-6096 (1991).
RN [8]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
RN [9]; RE0014859.
RX PUBMED: 1360810.
RA Langston A. W., Gudas L. J.
RT Identification of a retinoic acid responsive enhancer 3' of the murine homeobox gene Hox-1.6
RL Mech. Dev. 38:217-227 (1992).
RN [10]; RE0048057.
RX PUBMED: 16055921.
RA Martin P. J., Lardeux V., Lefebvre P.
RT The proliferating cell nuclear antigen regulates retinoic acid receptor transcriptional activity through direct protein-protein interaction.
RL Nucleic Acids Res. 33:4311-4321 (2005).
RN [11]; RE0051475.
RX PUBMED: 16805833.
RA Jeong H., Kim M. S., Kim S. W., Kim K. S., Seol W.
RT Regulation of tyrosine hydroxylase gene expression by retinoic acid receptor.
RL J. Neurochem 98:386-394 (2006).
RN [12]; RE0054989.
RX PUBMED: 15604093.
RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M.
RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
RL Mol. Cell. Proteomics 4:205-213 (2005).
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