AC T05984
XX
ID T05984
XX
DT 27.05.2004 (created); oke.
DT 09.11.2006 (updated); kau.
CO Copyright (C), QIAGEN.
XX
FA FosB
XX
SY FBJ murine osteosarcoma viral oncogene homolog B; FOSB; GOS3; GOSB.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G009540 FOSB; HGNC: FOSB.
XX
CL C0008; bZIP.
XX
SZ 338 AA; 36.0 kDa (cDNA) (calc.).
XX
SQ MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTA
SQ ITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGS
SQ GGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELT
SQ DRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRD
SQ LPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSY
SQ TSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAR
XX
SC translated from EMBL #L49169
XX
FT 153 217 SM00338; brlzneu.
FT 154 207 PF07716; Basic region leucine zipper.
FT 155 218 PS50217; BZIP.
XX
SF alternative splice variant is deltaFosB T05989;
XX
FF activator as a heterodimer with Jun factors;
FF binds to AP-1 sites;
FF in umbilical vein endothelial cells mRNA is induced by growth factors VEGF and PlGF [2];
XX
IN T00167 ATF-2-isoform1; human, Homo sapiens.
IN T09531 ATF-4; human, Homo sapiens.
IN T18798 ATFa-isoform3; human, Homo sapiens.
IN T08461 c-Jun; human, Homo sapiens.
IN T09550 CREBPA-Alpha; human, Homo sapiens.
IN T08989 Fra-1-isoform1; human, Homo sapiens.
IN T08491 JunB; human, Homo sapiens.
IN T08995 JunD; human, Homo sapiens.
IN T09646 MafB; human, Homo sapiens.
XX
MX M00517 V$AP1_01.
MX M00924 V$AP1_Q2_01.
MX M00926 V$AP1_Q4_01.
MX M00925 V$AP1_Q6_01.
XX
DR TRANSPATH: MO000042236.
DR EMBL: L49169;
DR UniProtKB: P53539;
XX
RN [1]; RE0024324.
RX PUBMED: 8985116.
RA Heximer S. P., Cristillo A. D., Russell L., Forsdyke D. R.
RT Sequence analysis and expression in cultured lymphocytes of the human FOSB gene (G0S3).
RL DNA Cell Biol. 15:1025-1038 (1996).
RN [2]; RE0024333.
RX PUBMED: 14741347.
RA Holmes D. I., Zachary I.
RT Placental growth factor induces FosB and c-Fos gene expression via Flt-1 receptors.
RL FEBS Lett. 557:93-98 (2004).
RN [3]; RE0048287.
RX PUBMED: 12805554.
RA Newman J. R., Keating A. E.
RT Comprehensive identification of human bZIP interactions with coiled-coil arrays.
RL Science 300:2097-2101 (2003).
XX
//