AC T06042
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ID T06042
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DT 19.07.2004 (created); cch.
DT 09.12.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA HDAC4
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SY HA6116; HD4; HDAC-A; HDACA; histone deacetylase 4; KIAA0288.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G007850 HDAC4; HGNC: HDAC4.
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IN T00040 AR; human, Homo sapiens.
IN T08300 ER-alpha-L; human, Homo sapiens.
IN T04110 HDAC3; human, Homo sapiens.
IN T08641 NCOR1-isoform1; mouse, Mus musculus.
IN T04687 NCOR1; human, Homo sapiens.
IN T04689 SMRT; human, Homo sapiens.
IN T04759 STAT1; human, Homo sapiens.
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DR TRANSPATH: MO000042975.
DR UniProtKB: P56524;
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RN [1]; RE0027552.
RX PUBMED: 10640275.
RA Huang E. Y., Zhang J., Miska E. A., Guenther M. G., Kouzarides T., Lazar M. A.
RT Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway.
RL Genes Dev. 14:45-54 (2000).
RN [2]; RE0029293.
RX PUBMED: 11804585.
RA Fischle W., Dequiedt F., Hendzel M. J., Guenther M. G., Lazar M. A., Voelter W., Verdin E.
RT Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
RL Mol. Cell 9:45-57 (2002).
RN [3]; RE0036029.
RX PUBMED: 11114188.
RA Zhou X., Richon V. M., Wang A. H., Yang X. J., Rifkind R. A., Marks P. A.
RT Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras.
RL Proc. Natl. Acad. Sci. USA 97:14329-14333 (2000).
RN [4]; RE0047460.
RX PUBMED: 15713663.
RA Fu M., Rao M., Bouras T., Wang C., Wu K., Zhang X., Li Z., Yao T. P., Pestell R. G.
RT Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
RL J. Biol. Chem. 280:16934-16941 (2005).
RN [5]; RE0062685.
RX PUBMED: 15778465.
RA Benzinger A., Muster N., Koch H. B., Yates JR 3. r. d., Hermeking H.
RT Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.
RL Mol. Cell. Proteomics 4:785-795 (2005).
RN [6]; RE0070489.
RX PUBMED: 21118993.
RA Cernotta N., Clocchiatti A., Florean C., Brancolini C.
RT Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility.
RL Mol. Biol. Cell 22:278-289 (2011).
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