AC T06145
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ID T06145
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DT 13.09.2004 (created); oke.
DT 30.07.2014 (updated); sla.
CO Copyright (C), QIAGEN.
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FA p73zeta
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SY tumor protein p73 isoform l; tumor suppressor p73, isoform zeta.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005523 TP73; HGNC: tp73.
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CL C0057; P53; 6.3.1.0.3.6.
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SZ 540 AA; 59.9 kDa (calc.).
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SQ MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
SQ VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
SQ YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
SQ YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
SQ EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
SQ DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
SQ GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPFLTGLGCPNCIEYFTSQGLQS
SQ IYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGE
SQ LQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
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SC Swiss-Prot#O15350-6
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FT 24 507 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 113 309 PF00870; P53 DNA-binding domain.
FT 345 386 PF07710; P53 tetramerisation motif.
FT 384 455 PF07647; SAM domain (Sterile alpha motif).
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SF several alternative products are known, p73alpha T04931, p73beta T06137, p73gamma T06142, p73delta T06143, p73epsilon T06144, p73zeta T06145, p73kappa T06139, p73eta T06179, DeltaN p73alpha T06002, DeltaN p73beta T06003, DeltaNp73gamma T06013;
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MX M00761 V$P53DECAMER_Q2.
MX M03558 V$P73_Q6.
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DR TRANSPATH: MO000043792.
DR UniProtKB: O15350-6;
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RN [1]; RE0024717.
RX PUBMED: 10381648.
RA De Laurenzi V. D., Catani M. V., Terrinoni A., Corazzari M., Melino G., Costanzo A., Levrero M., Knight R. A.
RT Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta.
RL Cell Death Differ. 6:389-390 (1999).
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