AC T08291
XX
ID T08291
XX
DT 22.11.2005 (created); oke.
DT 15.09.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA GATA-1-isoform1
XX
SY EF1; EFgammaa; Eryf-1; ERYF1; erythroid transcription factor; GATA-1; GF-1; NF-E1; NF-E1 (1).
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G000512 Gata1.
XX
CL C0004; CC; 2.2.1.1.1.1.
XX
SZ 413 AA; 42.7 kDa (cDNA) (calc.), 50 kDa (SDS)
XX
SQ MDFPGLGALGTSEPLPQFVDSALVSSPSDSTGFFSSGPEGLDAASSSTSPNAATAAASAL
SQ AYYREAEAYRHSPVFQVYPLLNSMEGIPGGSPYASWAYGKTALYPASTVCPSHEDAPSQA
SQ LEDQEGKSNNTFLDTLKTERLSPDLLTLGTALPASLPVTGSAYGGADFPSPFFSPTGSPL
SQ SSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP
SQ LIRPKKRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYFKLHQVNRPLTMRKD
SQ GIQTRNRKASGKGKKKRGSNLAGAGAAEGPAGGFMVVAGSSSSGNCGEVASGLALGTAGT
SQ AHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTTSFPTGPAPTTSSTSVIAPLSS
XX
SC translated from EMBL: X15763
XX
FT 1 66 
transcription activation domain Act1 [7].
FT 94 411 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 101 193 
transcription activation domain Act2 [8].
FT 198 248 
SM00401; ZnF_GATA.
FT 198 253 
PS50114; GATA_ZN_FINGER_2.
FT 204 238 
PF00320; GATA zinc finger.
FT 252 302 
SM00401; ZnF_GATA.
FT 252 305 
PS50114; GATA_ZN_FINGER_2.
FT 258 292 
PF00320; GATA zinc finger.
FT 308 413 
transcription activation domain Act3 [8].
XX
IN T00151 CP2-isoform1; human, Homo sapiens.
IN T19612 DRIP205; mouse, Mus musculus.
IN T09000 Fli-1-isoform1; human, Homo sapiens.
IN T08343 HDAC1; human, Homo sapiens.
IN T04110 HDAC3; human, Homo sapiens.
IN T08522 HDAC4-isoform1; human, Homo sapiens.
IN T08726 HDAC5-isoform1; human, Homo sapiens.
IN T01469 Ikaros-isoform1; mouse, Mus musculus.
IN T01472 Ikaros-isoform4; mouse, Mus musculus.
IN T19007 Ikaros-isoform6; mouse, Mus musculus.
IN T10037 PU.1; Mammalia.
XX
MX M00075 V$GATA1_01.
MX M00126 V$GATA1_02.
MX M00127 V$GATA1_03.
MX M00128 V$GATA1_04.
MX M00346 V$GATA1_05.
MX M00347 V$GATA1_06.
MX M02004 V$GATA1_Q6.
MX M00203 V$GATA_C.
MX M00789 V$GATA_Q6.
XX
BS R00518.
BS R00534.
BS R01944.
BS R02156.
BS R23352.
BS R23353.
BS R23354.
BS R38239.
BS R38240.
BS R00525.
BS R02889.
BS R38386.
BS R00550.
BS R01858.
BS R03116.
BS R01253.
BS R00540.
BS R00541.
BS R00543.
BS R35231.
BS R35368.
BS R35369.
BS R35370.
BS R35371.
BS R35372.
BS R35373.
BS R22290.
BS R03347.
BS R08260.
BS R03213.
BS R00507.
BS R00512.
BS R23029.
BS R03206.
BS R03207.
BS R03736.
BS R03737.
BS R23435.
BS R21700.
BS R20755.
BS R20756.
BS R01218.
XX
DR TRANSPATH: MO000056583.
DR EMBL: X15763;
DR EMBL: X57530;
DR UniProtKB: P17679;
XX
RN [1]; RE0000728.
RX PUBMED: 2276623.
RA Martin D. I. K., Orkin St. H.
RT Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1
RL Genes Dev. 4:1886-1898 (1990).
RN [2]; RE0004779.
RX PUBMED: 8524811.
RA Calligaris R., Bottardi S., Cogoi S., Apezteguia I., Santoro C.
RT Alternative translation initiation site usage results in two functionally distincts forms of the GATA-1 tanscription factor
RL Proc. Natl. Acad. Sci. USA 92:11598-11602 (1995).
RN [3]; RE0025804.
RX PUBMED: 14668799.
RA Watamoto K., Towatari M., Ozawa Y., Miyata Y., Okamoto M., Abe A., Naoe T., Saito H.
RT Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation.
RL Oncogene 22:9176-84 (2003).
RN [4]; RE0029104.
RX PUBMED: 11724781.
RA Crawford S. E., Qi C., Misra P., Stellmach V., Rao M. S., Engel J. D., Zhu Y., Reddy J. K.
RT Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.
RL J. Biol. Chem. 277:3585-92 (2002).
RN [5]; RE0034905.
RX PUBMED: 15173587.
RA Collavin L., Gostissa M., Avolio F., Secco P., Ronchi A., Santoro C., Del Sal G.
RT Modification of the erythroid transcription factor GATA-1 by SUMO-1.
RL Proc. Natl. Acad. Sci. USA 101:8870-5 (2004).
RN [6]; RE0037433.
RX PUBMED: 12724402.
RA Eisbacher M., Holmes M. L., Newton A., Hogg P. J., Khachigian L. M., Crossley M., Chong B. H.
RT Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding
RL Mol. Cell. Biol. 23:3427-41 (2003).
RN [7]; RE0003558.
RX PUBMED: 2481264.
RA Sobieszczuk P. W., Gonda T. J., Dunn A. R.
RT Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene
RL Nucleic Acids Res. 17:9593-9611 (1989).
RN [8]; RE0000688.
RX PUBMED: 1869051.
RA McCormick A., Brady H., Fukushima J., Karin M.
RT The pituitary-specific regulatory gene GHF1 contains a minimal cell type-specific promoter centered around its TATA-box
RL Genes Dev. 5:1490-1503 (1991).
XX
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