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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T33929 XX ID T33929 XX DT 10.04.2006 (created); man. DT 27.03.2012 (updated); yre. CO Copyright (C), QIAGEN. XX FA DRIP205-isoform1 XX SY Activator-recruited cofactor 205 kDa component; ARC205; DRIP205; p53 regulatory protein RB18A; PBP; peroxisome proliferator-activated receptor binding protein; Peroxisome proliferator-activated receptor-binding protein; PPAR binding protein; PPAR-binding protein; PPARBP; RB18A; thyroid hormone receptor interactor 2; Thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; Thyroid receptor-interacting protein 2; TRAP220; TRIP-2; TRIP2; vitamin D receptor-interacting protein complex component DRIP205. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004939 MED1; HGNC: MED1. XX SZ 1581 AA; 168.5 kDa (cDNA) (calc.). XX SQ MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS SQ CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL SQ CDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL SQ EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPI SQ ILHENNVSRSLGMNASVTIEGTSAVYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLP SQ ACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHN SQ MRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTL SQ IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY SQ KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL SQ PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ SQ NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL SQ YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ SQ NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT SQ DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD SQ LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS SQ QALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTT SQ GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK SQ SPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH SQ SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS SQ SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG SQ GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP SQ PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG SQ GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE SQ SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST SQ PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH SQ KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL SQ SPDFMIGEEDDDLMDVALIGN XX SC Swiss-Prot#Q15648-1 XX IN T08487 AR-isoform1; human, Homo sapiens. IN T08300 ER-alpha-L; human, Homo sapiens. IN T05299 NR1B1; human, Homo sapiens. IN T08255 PGC-1-isoform1; mouse, Mus musculus. IN T02726 PPARalpha; human, Homo sapiens. IN T05332 PPARgamma2; mouse, Mus musculus. IN T08433 RXR-alpha; human, Homo sapiens. IN T01152 T3R-alpha1; human, Homo sapiens. IN T08482 VDR-isoform1; human, Homo sapiens. XX DR TRANSPATH: MO000080002. DR EMBL: AF055994; DR EMBL: AF283812; AF283812. DR EMBL: L40366; DR EMBL: Y13467; DR UniProtKB: Q15648-1; XX RN [1]; RE0025974. RX PUBMED: 9653119. RA Yuan C. X., Ito M., Fondell J. D., Fu Z. Y., Roeder R. G. RT The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion RL Proc. Natl. Acad. Sci. USA 95:7939-44 (1998). RN [2]; RE0030588. RX PUBMED: 14636573. RA Wallberg A. E., Yamamura S., Malik S., Spiegelman B. M., Roeder R. G. RT Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. RL Mol. Cell 12:1137-49 (2003). RN [3]; RE0047548. RX PUBMED: 10733574. RA Rachez C., Gamble M., Chang C. P., Atkins G. B., Lazar M. A., Freedman L. P. RT The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes. RL Mol. Cell. Biol. 20:2718-2726 (2000). RN [4]; RE0053029. RX PUBMED: 12796488. RA Yamamoto H., Shevde N. K., Warrier A., Plum L. A., DeLuca H. F., Pike J. W. RT 2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts. RL J. Biol. Chem. 278:31756-31765 (2003). RN [5]; RE0073074. RX PUBMED: 22102282. RA Jin F., Claessens F., Fondell J. D. RT Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif. RL J. Biol. Chem. 287:858-870 (2012). XX //