AC T00292
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ID T00292
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DT 15.10.1992 (created); ewi.
DT 27.04.2015 (updated); smt.
CO Copyright (C), QIAGEN.
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FA Fra-1
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SY Fra-1; FraI.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006077 Fosl1.
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CL C0008; bZIP; 1.1.2.1.3.
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SF phosphorylation;
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CP Nrf2 knockout (F2) mouse fibroblasts [11].
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IN T01303 ATF-4; human, Homo sapiens.
IN T00051 ATF; human, Homo sapiens.
IN T00131 c-Jun; mouse, Mus musculus.
IN T00132 c-Jun; rat, Rattus norvegicus.
IN T00133 c-Jun; human, Homo sapiens.
IN T00134 c-Jun; chick, Gallus gallus.
IN T00135 c-Jun; hamster, Cricetulus sp.
IN T00436 JunB; mouse, Mus musculus.
IN T00437 JunD; mouse, Mus musculus.
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MX M00517 V$AP1_01.
MX M00924 V$AP1_Q2_01.
MX M00926 V$AP1_Q4_01.
MX M00925 V$AP1_Q6_01.
MX M01267 V$FRA1_Q5.
MX M02095 V$FRA1_Q6.
MX M03869 V$FRA1_Q6_01.
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BS R24899.
BS R23218.
BS R09882.
BS R25214.
BS R25215.
BS R01037.
BS R34245.
BS R41852.
BS R41854.
BS R41855.
BS R41858.
BS R36291.
BS R36293.
BS R36294.
BS R36295.
BS R36296.
BS R36297.
BS R36298.
BS R36299.
BS R35834.
BS R62535.
BS R21509.
BS R23479.
BS R72821.
BS R23477.
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DR TRANSPATH: MO000024841.
DR TRANSCOMPEL: C00499.
DR UniProtKB: P48755;
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RN [1]; RE0000656.
RX PUBMED: 2497053.
RA Cohen D. R., Ferreira P. C. P., Gentz R., Franza B. R., Curran T.
RT The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes
RL Genes Dev. 3:172-184 (1989).
RN [2]; RE0001698.
RX PUBMED: 3133553.
RA Cohen D. R., Curran T.
RT fra-1: a serum-inducible, cellular immediate-early gene that encodes a Fos-related antigen
RL Mol. Cell. Biol. 8:2063-2069 (1988).
RN [3]; RE0001770.
RX PUBMED: 2974122.
RA Kouzarides T., Ziff E.
RT The role of the leucine zipper in the fos-jun interaction
RL Nature 336:646-651 (1988).
RN [4]; RE0004628.
RX PUBMED: 8441422.
RA Boise L., Petryniak B., Mao X., June C. H., Wang C.-Y., Lindsten T., Bravo R., Kovary K., Leiden J., Thompson C. B.
RT The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB
RL Mol. Cell. Biol. 13:1911-1919 (1993).
RN [5]; RE0004643.
RX PUBMED: 8355695.
RA Kerppola T. K., Curran T.
RT Selective DNA bending by a variety of bZIP proteins
RL Mol. Cell. Biol. 13:5479-5489 (1993).
RN [6]; RE0004817.
RX PUBMED: 7504176.
RA Wisdom R., Verma I. M.
RT Transformation by Fos proteins requires a C-terminal transactivation domain
RL Mol. Cell. Biol. 13:7429-7438 (1993).
RN [7]; RE0004865.
RX PUBMED: 1406676.
RA Kovary K., Bravo R.
RT Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins
RL Mol. Cell. Biol. 12:5015-5023 (1992).
RN [8]; RE0004888.
RX PUBMED: 8070410.
RA Metz R., Kouzarides T., Bravo R.
RT A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth
RL EMBO J. 13:3832-3842 (1994).
RN [9]; RE0005861.
RX PUBMED: 8892610.
RA Huo L., Rothstein T. L.
RT Isolation and Characterization of Murine fra-1: Induction Mediated by CD40 and Surface Ig Is Protein Kinase Dependent
RL J. Immunol. 157:3812-3818 (1996).
RN [10]; RE0036098.
RX PUBMED: 11756554.
RA Young M. R., Nair R., Bucheimer N., Tulsian P., Brown N., Chapp C., Hsu T. C., Colburn N. H.
RT Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently.
RL Mol. Cell. Biol. 22:587-598 (2002).
RN [11]; RE0051710.
RX PUBMED: 15988009.
RA Yang H., Magilnick N., Lee C., Kalmaz D., Ou X., Chan J. Y., Lu S. C.
RT Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1.
RL Mol. Cell. Biol. 25:5933-5946 (2005).
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