TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T00292 XX ID T00292 XX DT 15.10.1992 (created); ewi. DT 27.04.2015 (updated); smt. CO Copyright (C), QIAGEN. XX FA Fra-1 XX SY Fra-1; FraI. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006077 Fosl1. XX CL C0008; bZIP; XX SF phosphorylation; XX CP Nrf2 knockout (F2) mouse fibroblasts [11]. XX IN T01303 ATF-4; human, Homo sapiens. IN T00051 ATF; human, Homo sapiens. IN T00131 c-Jun; mouse, Mus musculus. IN T00132 c-Jun; rat, Rattus norvegicus. IN T00133 c-Jun; human, Homo sapiens. IN T00134 c-Jun; chick, Gallus gallus. IN T00135 c-Jun; hamster, Cricetulus sp. IN T00436 JunB; mouse, Mus musculus. IN T00437 JunD; mouse, Mus musculus. XX MX M00517 V$AP1_01. MX M00924 V$AP1_Q2_01. MX M00926 V$AP1_Q4_01. MX M00925 V$AP1_Q6_01. MX M01267 V$FRA1_Q5. MX M02095 V$FRA1_Q6. MX M03869 V$FRA1_Q6_01. XX BS R24899. BS R23218. BS R09882. BS R25214. BS R25215. BS R01037. BS R34245. BS R41852. BS R41854. BS R41855. BS R41858. BS R36291. BS R36293. BS R36294. BS R36295. BS R36296. BS R36297. BS R36298. BS R36299. BS R35834. BS R62535. BS R21509. BS R23479. BS R72821. BS R23477. XX DR TRANSPATH: MO000024841. DR TRANSCOMPEL: C00499. DR UniProtKB: P48755; XX RN [1]; RE0000656. RX PUBMED: 2497053. RA Cohen D. R., Ferreira P. C. P., Gentz R., Franza B. R., Curran T. RT The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes RL Genes Dev. 3:172-184 (1989). RN [2]; RE0001698. RX PUBMED: 3133553. RA Cohen D. R., Curran T. RT fra-1: a serum-inducible, cellular immediate-early gene that encodes a Fos-related antigen RL Mol. Cell. Biol. 8:2063-2069 (1988). RN [3]; RE0001770. RX PUBMED: 2974122. RA Kouzarides T., Ziff E. RT The role of the leucine zipper in the fos-jun interaction RL Nature 336:646-651 (1988). RN [4]; RE0004628. RX PUBMED: 8441422. RA Boise L., Petryniak B., Mao X., June C. H., Wang C.-Y., Lindsten T., Bravo R., Kovary K., Leiden J., Thompson C. B. RT The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB RL Mol. Cell. Biol. 13:1911-1919 (1993). RN [5]; RE0004643. RX PUBMED: 8355695. RA Kerppola T. K., Curran T. RT Selective DNA bending by a variety of bZIP proteins RL Mol. Cell. Biol. 13:5479-5489 (1993). RN [6]; RE0004817. RX PUBMED: 7504176. RA Wisdom R., Verma I. M. RT Transformation by Fos proteins requires a C-terminal transactivation domain RL Mol. Cell. Biol. 13:7429-7438 (1993). RN [7]; RE0004865. RX PUBMED: 1406676. RA Kovary K., Bravo R. RT Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins RL Mol. Cell. Biol. 12:5015-5023 (1992). RN [8]; RE0004888. RX PUBMED: 8070410. RA Metz R., Kouzarides T., Bravo R. RT A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth RL EMBO J. 13:3832-3842 (1994). RN [9]; RE0005861. RX PUBMED: 8892610. RA Huo L., Rothstein T. L. RT Isolation and Characterization of Murine fra-1: Induction Mediated by CD40 and Surface Ig Is Protein Kinase Dependent RL J. Immunol. 157:3812-3818 (1996). RN [10]; RE0036098. RX PUBMED: 11756554. RA Young M. R., Nair R., Bucheimer N., Tulsian P., Brown N., Chapp C., Hsu T. C., Colburn N. H. RT Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. RL Mol. Cell. Biol. 22:587-598 (2002). RN [11]; RE0051710. RX PUBMED: 15988009. RA Yang H., Magilnick N., Lee C., Kalmaz D., Ou X., Chan J. Y., Lu S. C. RT Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1. RL Mol. Cell. Biol. 25:5933-5946 (2005). XX //