TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T00437 XX ID T00437 XX DT 15.10.1992 (created); ewi. DT 05.02.2015 (updated); pro. CO Copyright (C), QIAGEN. XX FA JunD XX SY Jun-D; JUND1; TRANSCRIPTION FACTOR JUN-D. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G000545 Jund. XX CL C0008; bZIP; XX SF relatively poor sequence conservation with human JunD [11]; XX CP widespread expression at differing levels [10]; wild type mouse fibroblasts, Nrf1 (F1) and Nrf2 (F2) knockout mouse fibroblasts [17]; FSDC and FSDC + antiCD40 [15]. XX FF no detectable transforming activity [7]; FF antagonist to transforming effects of the Ras - c-Jun pathway [12]; FF no inhibition of myogenic effects of MyoD or myogenin [6]; FF expressed at a higher level than c-Jun and JunB in nongrowing cells (3T3) [10]; FF expression is only slightly stimulated by growth factors in late G12 phase [10]; FF resynthesis following quick degradation of nuclear JunD after serum stimulation [12]; FF activation by JunD may depend on PKA and s antagonized by JunB+c-Fos [9]; XX IN T00122 c-Fos; mouse, Mus musculus. IN T00123 c-Fos; human, Homo sapiens. IN T00124 c-Fos; rat, Rattus norvegicus. IN T00125 c-Fos; chick, Gallus gallus. IN T02198 deltaFosB; mouse, Mus musculus. IN T00291 FosB; mouse, Mus musculus. IN T00292 Fra-1; mouse, Mus musculus. IN T01208 Fra-1; rat, Rattus norvegicus. IN T01990 Fra-2; chick, Gallus gallus. IN T01991 Fra-2; human, Homo sapiens. IN T00436 JunB; mouse, Mus musculus. IN T00437 JunD; mouse, Mus musculus. XX MX M00517 V$AP1_01. MX M00924 V$AP1_Q2_01. MX M00926 V$AP1_Q4_01. MX M00925 V$AP1_Q6_01. MX M03552 V$JUND_Q6. XX BS R02666. BS R25217. BS R02667. BS R23219. BS R09882. BS R22860. BS R25855. BS R73762. BS R73824. BS R34234. BS R37586. BS R37826. BS R66081. BS R04079. BS R04032. BS R37213. BS R40188. BS R02096. BS R08510. BS R35834. BS R13173. BS R13176. BS R21509. BS R23478. BS R41865. BS R64219. BS R01225. BS R35124. BS R35353. XX DR TRANSPATH: MO000007835. DR UniProtKB: P15066; XX RN [1]; RE0000143. RX PUBMED: 3142691. RA Nakabeppu Y., Ryder K., Nathans D. RT DNA Binding Activities of Three Murine Jun Proteins: Stimulation by Fos RL Cell 55:907-915 (1988). RN [2]; RE0000396. RX PUBMED: 2504580. RA Hirai S.-I., Ryseck R.-P., Mechta F., Bravo R., Yaniv M. RT Characterization of junD: a new member of the jun proto-oncogene family RL EMBO J. 8:1433-1439 (1989). RN [3]; RE0000442. RX PUBMED: 2511004. RA Nakabeppu Y., Nathans D. RT The basic region of Fos mediates specific DNA binding RL EMBO J. 8:3833-3841 (1989). RN [4]; RE0000521. RX PUBMED: 1714380. RA de Groot R. P., Karperien M., Pals C., Kruijer W. RT Characterization of the mouse junD promoter - high basal level activity due to an octamer motif RL EMBO J. 10:2523-2532 (1991). RN [5]; RE0002365. RX PUBMED: 3422745. RA Ryder K., Lau L. F., Nathans D. RT A gene activated by growth factor is related to the oncogene v-jun RL Proc. Natl. Acad. Sci. USA 85:1487-1491 (1988). RN [6]; RE0003225. RX PUBMED: 1313772. RA Li L., Chambard J. C., Karin M., Olson E. N. RT Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression RL Genes Dev. 6:676-689 (1992). RN [7]; RE0004679. RX PUBMED: 1924349. RA Castellazzi M., Spyrou G., La Vista N., Dangy J.-P., Piu F., Yaniv M., Brun G. RT Overexpression of c-jun, junB, or junD affects cell growth differently RL Proc. Natl. Acad. Sci. USA 88:8890-8894 (1991). RN [8]; RE0004737. RX PUBMED: 1945831. RA Suzuki T., Okuno H., Yoshida T., Endo T., Nishina H., Iba H. RT Difference in transcriptional regulatory function between c-Fos and Fra-2 RL Nucleic Acids Res. 19:5537-5542 (1991). RN [9]; RE0004740. RX PUBMED: 1719551. RA Kobierski L. A., Chu H. M., Tan Y., Comb M. J. RT cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins RL Proc. Natl. Acad. Sci. USA 88:10222-10226 (1991). RN [10]; RE0004783. RX PUBMED: 2493644. RA Ryder K., Lanahan A., Perez-Albuerne E., Nathans D. RT Jun-D: A third member of the Jun gene family RL Proc. Natl. Acad. Sci. USA 86:1500-1503 (1989). RN [11]; RE0004786. RX PUBMED: 1903194. RA Berger I., Shaul Y. RT Structure and function of human jun-D RL Oncogene 6:561-566 (1991). RN [12]; RE0004792. RX PUBMED: 8124713. RA Pfarr C. M., Mechta F., Spyrou G., Lallemand D., Carillo S., Yaniv M. RT Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras RL Cell 76:747-760 (1994). RN [13]; RE0004882. RX PUBMED: 1900040. RA Nakabeppu Y., Nathans D. RT A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity RL Cell 64:751-759 (1991). RN [14]; RE0019485. RX PUBMED: 2104845. RA LI L., HU J.-S., OLSON E.N. RT Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor. RL J. Biol. Chem. 265:1556-1562 (1990). RN [15]; RE0025717. RX PUBMED: 11886848. RA Mann J., Oakley F., Johnson P. W., Mann D. A. RT CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1. RL J. Biol. Chem. 277:17125-38 (2002). RN [16]; RE0036098. RX PUBMED: 11756554. RA Young M. R., Nair R., Bucheimer N., Tulsian P., Brown N., Chapp C., Hsu T. C., Colburn N. H. RT Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. RL Mol. Cell. Biol. 22:587-598 (2002). RN [17]; RE0051710. RX PUBMED: 15988009. RA Yang H., Magilnick N., Lee C., Kalmaz D., Ou X., Chan J. Y., Lu S. C. RT Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1. RL Mol. Cell. Biol. 25:5933-5946 (2005). XX //