AC T00524
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ID T00524
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DT 21.10.1992 (created); ewi.
DT 13.12.2006 (updated); kau.
CO Copyright (C), QIAGEN.
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FA MyoD
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SY MyoD; XMyoD.
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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GE G001913 MyoD.
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CL C0010; bHLH; 1.2.2.1.1.
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SF the heterodimer with E12/E47 is identical with the DNA-binding activity EMF1 [6] [2];
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CP precursors of skeletal muscle cells.
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FF myogenic factor, expressed in early response to mesoderm induction [4] [1];
FF in midblastula transition stage: ubiquitous low-level expression [5];
FF for induction of full myogenic differentiation, additional factors are required [3];
FF regulated nuclear localization in myogenic cells [6];
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IN T00204 E12; human, Homo sapiens.
IN T00207 E47; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T00404 Id2; mouse, Mus musculus.
IN T01212 Id2; human, Homo sapiens.
IN T00432 ITF-1; human, Homo sapiens.
IN T00433 ITF-2; human, Homo sapiens.
IN T00526 MyoD; mouse, Mus musculus.
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MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M00001 V$MYOD_01.
MX M00184 V$MYOD_Q6.
MX M00929 V$MYOD_Q6_01.
MX M02100 V$MYOD_Q6_02.
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BS R02208.
BS R03329.
BS R03330.
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DR TRANSPATH: MO000024988.
DR UniProtKB: P13904;
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RN [1]; RE0000473.
RX PUBMED: 2555164.
RA Hopwood N. D., Pluck A., Gurdon J. B.
RT MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos
RL EMBO J. 8:3409-3417 (1989).
RN [2]; RE0000759.
RX PUBMED: 1648530.
RA Taylor M. V., Gurdon J. B., Hopwood N. D., Towers N., Mohun T. J.
RT Xenopus embryos contain a somite-specific, MyoD-like protein that binds to a promoter site required for muscle actin expression
RL Genes Dev. 5:1149-1160 (1991).
RN [3]; RE0003219.
RX PUBMED: 1697650.
RA Hopwood N. D., Gurdon J. B.
RT Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo
RL Nature 347:197-200 (1990).
RN [4]; RE0003220.
RX PUBMED: 1656464.
RA Harvey R. P.
RT Widespread expression of MyoD genes in Xenopus embryos is amplified in presumptive muscle as a delayed response to mesoderm induction
RL Proc. Natl. Acad. Sci. USA 88:9198-9202 (1991).
RN [5]; RE0003221.
RX PUBMED: 1675156.
RA Rupp R. A. W., Weintraub H.
RT Ubiquitous MyoD transcription at the midblastula transition precedes induction-independent MyoD expression in presumptive mesoderm of Xenopus laevis
RL Cell 65:927-937 (1991).
RN [6]; RE0003224.
RX PUBMED: 1322293.
RA Rashbass J., Taylor M. V., Gurdon J. B.
RT The DNA-binding protein E12 co-operates with XMyoD in the activation of muscle-specific gene expression in Xenopus embryos
RL EMBO J. 11:2981-2990 (1992).
RN [7]; RE0003243.
RX PUBMED: 7926732.
RA Rupp R. A. W., Snider L., Weintraub H.
RT Xenopus embryos regulate the nuclear localization of XMyoD
RL Genes Dev. 8:1311-1323 (1994).
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