TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01114 XX ID T01114 XX DT 15.03.1994 (created); ewi. DT 26.05.2015 (updated); msr. CO Copyright (C), QIAGEN. XX FA C/EBPdelta XX SY C/EBPdelta; CCAAT Enhancer Binding Protein delta; CELF; CRP3; NF-IL6beta. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002533 Cebpd. XX CL C0008; bZIP; XX SF same DNA-binding specificity as C/EBPbeta / NF-IL6; XX CP ubiquitous [3]; Nucleus of WEHI 3BD [12]. XX FF strong transcription activator, synergistically acting with NF-kappaB, presumably by physical interaction [5]; FF expressed very early during adipocyte differentiation, can be induced by adipogenic hormones; FF expression declines before onset of C/EBPalpha accumulation [2]; FF insulin transiently induces C/EBPdelta in fully-differentiated adipocytes [6]; FF greatly enhanced activity after phosphorylation [4]; XX IN T08443 AML3; mouse, Mus musculus. IN T00104 C/EBPalpha-isoform1; mouse, Mus musculus. IN T00108 C/EBPalpha-isoform1; rat, Rattus norvegicus. IN T00105 C/EBPalpha; human, Homo sapiens. IN T00017 C/EBPbeta-FL; mouse, Mus musculus. IN T00459 C/EBPbeta-FL; rat, Rattus norvegicus. IN T00581 C/EBPbeta; human, Homo sapiens. IN T01114 C/EBPdelta; mouse, Mus musculus. XX MX M07316 V$CEBPD_Q3. MX M00621 V$CEBPD_Q6. MX M03571 V$CEBPD_Q6_01. MX M00912 V$CEBP_Q2_01. MX M00770 V$CEBP_Q3. XX BS R00207. BS R22149. BS R32278. BS R23644. BS R14487. BS R08091. BS R08092. BS R71976. BS R72489. BS R21771. BS R26269. BS R23524. BS R21754. BS R08130. BS R29474. BS R13172. BS R39010. BS R26718. BS R60360. BS R67929. BS R67930. BS R13310. BS R13311. BS R23087. BS R29343. BS R59358. BS R73939. BS R00097. XX DR TRANSPATH: MO000002643. DR TRANSCOMPEL: C00104. DR TRANSCOMPEL: C00148. DR TRANSCOMPEL: C00608. DR EMBL: M85144; DR EMBL: X61800; DR UniProtKB: Q00322; XX RN [1]; RE0000742. RX PUBMED: 1884998. RA Williams S. C., Cantwell C. A., Johnson P. F. RT A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro RL Genes Dev. 5:1553-1567 (1991). RN [2]; RE0002732. RX PUBMED: 1840554. RA Cao Z., Umek R. M., McKnight S. L. RT Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells RL Genes Dev. 5:1538-1552 (1991). RN [3]; RE0003023. RX PUBMED: 1371993. RA Alam T., An M. R., Papaconstantinou J. RT Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response RL J. Biol. Chem. 267:5021-5024 (1992). RN [4]; RE0003032. RX PUBMED: 8196668. RA Ray A., Ray B. K. RT Serum amyloid A gene expression under acute-phase conditions involves participation of inducible C/EBP-beta and C/EBP-delta and their activation by phosphorylation RL Mol. Cell. Biol. 14:4324-4332 (1994). RN [5]; RE0004524. RX PUBMED: 8321203. RA Stein B., Cogswell P. C., Baldwin jr A. S. RT Functional and physical associations between NF-kappaB and C/EBP family members: a Rel domain-bZIP interaction RL Mol. Cell. Biol. 13:3964-3974 (1993). RN [6]; RE0011717. RX PUBMED: 7822291. RA Dougald O. A. Mac, Cornelius P., Liu R., Lane M. D. RT Insulin regulates transcription of the CCAAT/Enhancer binding protein (C/EBP) alpha, beta and delta genes in fully-differentiated 3T3-L1 adipocytes RL J. Biol. Chem. 270:647-654 (1995). RN [7]; RE0028650. RX PUBMED: 11012671. RA Jung N., Yi Y. W., Kim D., Shong M., Hong S. S., Lee H. S., Bae I. RT Regulation of Gadd45gamma expression by C/EBP. RL Eur. J. Biochem. 267:6180-7 (2000). RN [8]; RE0047660. RX PUBMED: 12727880. RA Wiper-Bergeron N., Wu D., Pope L., Schild-Poulter C., Hache R. J. RT Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex. RL EMBO J. 22:2135-2145 (2003). RN [9]; RE0048262. RX PUBMED: 16210377. RA Singh R., Artaza J. N., Taylor W. E., Braga M., Yuan X., Gonzalez-Cadavid N. F., Bhasin S. RT Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. RL Endocrinology 147:141-154 (2006). RN [10]; RE0064596. RX PUBMED: 17456598. RA Maitra A., Shen F., Hanel W., Mossman K., Tocker J., Swart D., Gaffen S. L. RT Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. RL Proc. Natl. Acad. Sci. USA 104:7506-7511 (2007). RN [11]; RE0065417. RX PUBMED: 19454718. RA Lu Y. C., Kim I., Lye E., Shen F., Suzuki N., Suzuki S., Gerondakis S., Akira S., Gaffen S. L., Yeh W. C., Ohashi P. S. RT Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines. RL J. Immunol. 182:7212-7221 (2009). RN [12]; RE0034223. RX PUBMED: 8855267. RA Ford A. M., Bennett C. A., Healy L. E., Towatari M., Greaves M. F., Enver T. RT Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification. RL Proc. Natl. Acad. Sci. USA 93:10838-43 (1996). XX //