AC T01114
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ID T01114
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DT 15.03.1994 (created); ewi.
DT 26.05.2015 (updated); msr.
CO Copyright (C), QIAGEN.
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FA C/EBPdelta
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SY C/EBPdelta; CCAAT Enhancer Binding Protein delta; CELF; CRP3; NF-IL6beta.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002533 Cebpd.
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CL C0008; bZIP; 1.1.8.1.4.
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SF same DNA-binding specificity as C/EBPbeta / NF-IL6;
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CP ubiquitous [3]; Nucleus of WEHI 3BD [12].
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FF strong transcription activator, synergistically acting with NF-kappaB, presumably by physical interaction [5];
FF expressed very early during adipocyte differentiation, can be induced by adipogenic hormones;
FF expression declines before onset of C/EBPalpha accumulation [2];
FF insulin transiently induces C/EBPdelta in fully-differentiated adipocytes [6];
FF greatly enhanced activity after phosphorylation [4];
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IN T08443 AML3; mouse, Mus musculus.
IN T00104 C/EBPalpha-isoform1; mouse, Mus musculus.
IN T00108 C/EBPalpha-isoform1; rat, Rattus norvegicus.
IN T00105 C/EBPalpha; human, Homo sapiens.
IN T00017 C/EBPbeta-FL; mouse, Mus musculus.
IN T00459 C/EBPbeta-FL; rat, Rattus norvegicus.
IN T00581 C/EBPbeta; human, Homo sapiens.
IN T01114 C/EBPdelta; mouse, Mus musculus.
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MX M07316 V$CEBPD_Q3.
MX M00621 V$CEBPD_Q6.
MX M03571 V$CEBPD_Q6_01.
MX M00912 V$CEBP_Q2_01.
MX M00770 V$CEBP_Q3.
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BS R00207.
BS R22149.
BS R32278.
BS R23644.
BS R14487.
BS R08091.
BS R08092.
BS R71976.
BS R72489.
BS R21771.
BS R26269.
BS R23524.
BS R21754.
BS R08130.
BS R29474.
BS R13172.
BS R39010.
BS R26718.
BS R60360.
BS R67929.
BS R67930.
BS R13310.
BS R13311.
BS R23087.
BS R29343.
BS R59358.
BS R73939.
BS R00097.
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DR TRANSPATH: MO000002643.
DR TRANSCOMPEL: C00104.
DR TRANSCOMPEL: C00148.
DR TRANSCOMPEL: C00608.
DR EMBL: M85144;
DR EMBL: X61800;
DR UniProtKB: Q00322;
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RN [1]; RE0000742.
RX PUBMED: 1884998.
RA Williams S. C., Cantwell C. A., Johnson P. F.
RT A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro
RL Genes Dev. 5:1553-1567 (1991).
RN [2]; RE0002732.
RX PUBMED: 1840554.
RA Cao Z., Umek R. M., McKnight S. L.
RT Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
RL Genes Dev. 5:1538-1552 (1991).
RN [3]; RE0003023.
RX PUBMED: 1371993.
RA Alam T., An M. R., Papaconstantinou J.
RT Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response
RL J. Biol. Chem. 267:5021-5024 (1992).
RN [4]; RE0003032.
RX PUBMED: 8196668.
RA Ray A., Ray B. K.
RT Serum amyloid A gene expression under acute-phase conditions involves participation of inducible C/EBP-beta and C/EBP-delta and their activation by phosphorylation
RL Mol. Cell. Biol. 14:4324-4332 (1994).
RN [5]; RE0004524.
RX PUBMED: 8321203.
RA Stein B., Cogswell P. C., Baldwin jr A. S.
RT Functional and physical associations between NF-kappaB and C/EBP family members: a Rel domain-bZIP interaction
RL Mol. Cell. Biol. 13:3964-3974 (1993).
RN [6]; RE0011717.
RX PUBMED: 7822291.
RA Dougald O. A. Mac, Cornelius P., Liu R., Lane M. D.
RT Insulin regulates transcription of the CCAAT/Enhancer binding protein (C/EBP) alpha, beta and delta genes in fully-differentiated 3T3-L1 adipocytes
RL J. Biol. Chem. 270:647-654 (1995).
RN [7]; RE0028650.
RX PUBMED: 11012671.
RA Jung N., Yi Y. W., Kim D., Shong M., Hong S. S., Lee H. S., Bae I.
RT Regulation of Gadd45gamma expression by C/EBP.
RL Eur. J. Biochem. 267:6180-7 (2000).
RN [8]; RE0047660.
RX PUBMED: 12727880.
RA Wiper-Bergeron N., Wu D., Pope L., Schild-Poulter C., Hache R. J.
RT Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex.
RL EMBO J. 22:2135-2145 (2003).
RN [9]; RE0048262.
RX PUBMED: 16210377.
RA Singh R., Artaza J. N., Taylor W. E., Braga M., Yuan X., Gonzalez-Cadavid N. F., Bhasin S.
RT Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors.
RL Endocrinology 147:141-154 (2006).
RN [10]; RE0064596.
RX PUBMED: 17456598.
RA Maitra A., Shen F., Hanel W., Mossman K., Tocker J., Swart D., Gaffen S. L.
RT Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression.
RL Proc. Natl. Acad. Sci. USA 104:7506-7511 (2007).
RN [11]; RE0065417.
RX PUBMED: 19454718.
RA Lu Y. C., Kim I., Lye E., Shen F., Suzuki N., Suzuki S., Gerondakis S., Akira S., Gaffen S. L., Yeh W. C., Ohashi P. S.
RT Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines.
RL J. Immunol. 182:7212-7221 (2009).
RN [12]; RE0034223.
RX PUBMED: 8855267.
RA Ford A. M., Bennett C. A., Healy L. E., Towatari M., Greaves M. F., Enver T.
RT Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification.
RL Proc. Natl. Acad. Sci. USA 93:10838-43 (1996).
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