AC T01128
XX
ID T01128
XX
DT 17.04.1994 (created); ewi.
DT 12.01.2009 (updated); ask.
CO Copyright (C), QIAGEN.
XX
FA MyoD
XX
SY CMD1; MEF1; Myf-3 (human); MyoD; MyoD1.
XX
OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
XX
GE G057543 MYOD1.
XX
CL C0010; bHLH; 1.2.2.1.1.
XX
SF the side chains that define the dimerization specificity between MyoD and E12 have been identified [5];
XX
CP skeletal muscle, floor plate/notochord [7].
XX
FF serine phosphorylation enhances DNA-binding by MyoD/E12 heterodimers, but represses that of MyoD homodimers [6];
FF induced by Shh (Sonic hedgehog) in the neural tube lacking floor plate [7];
XX
IN T00134 c-Jun; chick, Gallus gallus.
IN T00204 E12; human, Homo sapiens.
IN T00207 E47; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T00404 Id2; mouse, Mus musculus.
IN T01212 Id2; human, Homo sapiens.
IN T00432 ITF-1; human, Homo sapiens.
IN T00433 ITF-2; human, Homo sapiens.
IN T00526 MyoD; mouse, Mus musculus.
XX
MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M00001 V$MYOD_01.
MX M00184 V$MYOD_Q6.
MX M00929 V$MYOD_Q6_01.
MX M02100 V$MYOD_Q6_02.
XX
BS R01620.
BS R02208.
XX
DR TRANSPATH: MO000025423.
DR UniProtKB: P16075;
XX
RN [1]; RE0003215.
RX PUBMED: 2748593.
RA Weintraub H., Tapscott S. J., Davis R. L., Thayer M. J., Adam M. A., Lassar A. B., Miller A. D.
RT Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD
RL Proc. Natl. Acad. Sci. USA 86:5434-5438 (1989).
RN [2]; RE0003229.
RX PUBMED: 2777078.
RA Lin Z. Y., Dechesne C. A., Eldridge J., Paterson B. M.
RT An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts
RL Genes Dev. 3:986-996 (1989).
RN [3]; RE0003230.
RX PUBMED: 8035824.
RA Dechesne C. A., Wei Q., Eldridge J., Gannoun-Zaki L., Millasseau P., Bougueleret L., Caterina D., Paterson B. M.
RT E-box- and MEF-2-independent muscle-specific expression, positive autoregulation, and cross-activation of the chicken MyoD (CMD1) promoter reveal an indirect regulatory pathway
RL Mol. Cell. Biol. 14:5474-5486 (1994).
RN [4]; RE0003233.
RX PUBMED: 8389359.
RA Nakamura S.
RT Possible role of phosphorylation in the function of chicken MyoD1
RL J. Biol. Chem. 268:11670-11677 (1993).
RN [5]; RE0003235.
RX PUBMED: 8253390.
RA Shirakata M., Friedman F. K., Wei Q., Paterson B. M.
RT Dimerization specificity of myogenic helix-loop-helix DNA-binding factors directed by nonconserved hydrophilic residues
RL Genes Dev. 7:2456-2470 (1993).
RN [6]; RE0003237.
RX PUBMED: 8226992.
RA Mitsui K., Shirakata M., Paterson B. M.
RT Phosphorylation inhibits the DNA-binding activity of MyoD homodimers but not MyoD-E12 heterodimers
RL J. Biol. Chem. 268:24415-24420 (1993).
RN [7]; RE0005815.
RX PUBMED: 7498788.
RA Muensterberg A. E., Kitajewski J., Bumcrot D.A., McMahon A. P., Lassar A. B.
RT Combinatorial signaling by sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite
RL Genes Dev. 9:2911-2922 (1995).
XX
//