TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01487 XX ID T01487 XX DT 08.05.1995 (created); ewi. DT 16.04.2014 (updated); pos. CO Copyright (C), QIAGEN. XX FA cyclinA XX SY CCNA. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX FF regulating component of a DNA-binding complex; XX IN T04074 brca1; human, Homo sapiens. IN T01488 Cdk2; human, Homo sapiens. IN T00221 E2F:DP; human, Homo sapiens. IN T34275 mcm5; human, Homo sapiens. IN T01804 NF-YA; human, Homo sapiens. IN T01486 p107; human, Homo sapiens. IN T01608 p130; human, Homo sapiens. IN T34034 p21Cip1; human, Homo sapiens. IN T01661 PR A; human, Homo sapiens. IN T00696 PR B; human, Homo sapiens. XX BS R01801. XX DR TRANSPATH: MO000021735. XX RN [1]; RE0002985. RX PUBMED: 1328853. RA Wade M., Kowalik T. F., Mudryj M., Huang E.-S., Azizkhan J. C. RT E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection RL Mol. Cell. Biol. 12:4364-4374 (1992). RN [2]; RE0017514. RX PUBMED: 11584018. RA Santaguida M., Ding Q., Berube G., Truscott M., Whyte P., Nepveu A. RT Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2). RL J. Biol. Chem. 276:45780-45790 (2001). RN [3]; RE0025710. RX PUBMED: 11867521. RA Wang H., Goode T., Iakova P., Albrecht J. H., Timchenko N. A. RT C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest. RL EMBO J. 21:930-41 (2002). RN [4]; RE0034390. RX PUBMED: 15014502. RA Bashir T., Dorrello N. V., Amador V., Guardavaccaro D., Pagano M. RT Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. RL Nature 428:190-3 (2004). RN [5]; RE0048082. RX PUBMED: 9244350. RA Wang H., Shao N., Ding Q. M., Cui J., Reddy E. S., Rao V. N. RT BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases. RL Oncogene 15:143-157 (1997). RN [6]; RE0049718. RX PUBMED: 15558010. RA Rape M., Kirschner M. W. RT Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry. RL Nature 432:588-595 (2004). RN [7]; RE0050210. RX PUBMED: 17485488. RA Di Fiore B., Pines J. RT Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C. RL J. Cell Biol. 177:425-437 (2007). RN [8]; RE0050272. RX PUBMED: 16460673. RA Khwaja F., Tabassum A., Allen J., Djakiew D. RT The p75(NTR) tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells. RL Biochem. Biophys. Res. Commun. 341:1184-1192 (2006). RN [9]; RE0051102. RX PUBMED: 16951159. RA Hiramatsu Y., Kitagawa K., Suzuki T., Uchida C., Hattori T., Kikuchi H., Oda T., Hatakeyama S., Nakayama K. I., Yamamoto T., Konno H., Kitagawa M. RT Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination. RL Cancer Res. 66:8477-8483 (2006). RN [10]; RE0052419. RX PUBMED: 17468517. RA Saegusa M., Hashimura M., Kuwata T., Hamano M., Wani Y., Okayasu I. RT A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas. RL Carcinogenesis 28:1885-1892 (2007). RN [11]; RE0053292. RX PUBMED: 15601848. RA Narayanan R., Adigun A. A., Edwards D. P., Weigel N. L. RT Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. RL Mol. Cell. Biol. 25:264-277 (2005). RN [12]; RE0062791. RX PUBMED: 17698606. RA Tsang W. Y., Wang L., Chen Z., Sanchez I., Dynlacht B. D. RT SCAPER, a novel cyclin A-interacting protein that regulates cell cycle progression. RL J. Cell Biol. 178:621-633 (2007). RN [13]; RE0066515. RX PUBMED: 8668211. RA Tiefenbrun N., Melamed D., Levy N., Resnitzky D., Hoffman I., Reed S. I., Kimchi A. RT Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. RL Mol. Cell. Biol. 16:3934-3944 (1996). RN [14]; RE0066800. RX PUBMED: 20220142. RA Por E., Byun H. J., Lee E. J., Lim J. H., Jung S. Y., Park I., Kim Y. M., Jeoung D. I., Lee H. RT The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner. RL J. Biol. Chem. 285:14475-14485 (2010). RN [15]; RE0070681. RX PUBMED: 19858290. RA Li C., Andrake M., Dunbrack R., Enders G. H. RT A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export. RL Mol. Cell. Biol. 30:116-130 (2010). XX //