AC T14288
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ID T14288
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DT 17.03.2006 (created); man.
DT 05.01.2016 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA PLZF
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SY PLZF; PLZF(m.s); promyelocytic leukemia zinc finger; Zinc finger protein 145; Zinc finger protein PLZF.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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FF Doxycycline exerts tight repression of PLZF [6];
FF PLZF represses the expression of BID and mediates the increased resistance to serum deprivation-induced apoptosis. [6];
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IN T00040 AR; human, Homo sapiens.
IN T21852 HDAC1; Mammalia.
IN T23418 HDAC1; mouse, Mus musculus.
IN T23091 p300; Mammalia.
IN T25008 pRb; Mammalia.
IN T17580 SATB1; mouse, Mus musculus.
IN T00752 Sp1; mouse, Mus musculus.
IN T08326 Sp1; Mammalia.
IN T08482 VDR-isoform1; human, Homo sapiens.
IN T31896 VDR; Mammalia.
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MX M04625 V$PLZFB_Q3.
MX M01075 V$PLZF_02.
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BS R32081.
BS R23900.
BS R66970.
BS R66971.
BS R66972.
BS R26658.
BS R26659.
BS R38777.
BS R26651.
BS R26634.
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DR TRANSPATH: MO000079338.
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RN [1]; RE0044001.
RX PUBMED: 14657020.
RA Senbonmatsu T., Saito T., Landon E. J., Watanabe O., Price E. Jr, Roberts R. L., Imboden H., Fitzgerald T. G., Gaffney F. A., Inagami T.
RT A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy
RL EMBO J. 22:6471-82 (2003).
RN [2]; RE0047451.
RX PUBMED: 12460926.
RA Puccetti E., Obradovic D., Beissert T., Bianchini A., Washburn B., Chiaradonna F., Boehrer S., Hoelzer D., Ottmann O. G., Pelicci P. G., Nervi C., Ruthardt M.
RT AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
RL Cancer Res. 62:7050-7058 (2002).
RN [3]; RE0047504.
RX PUBMED: 15964811.
RA Guidez F., Howell L., Isalan M., Cebrat M., Alani R. M., Ivins S., Hormaeche I., McConnell M. J., Pierce S., Cole P. A., Licht J., Zelent A.
RT Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.
RL Mol. Cell. Biol. 25:5552-5566 (2005).
RN [4]; RE0047618.
RX PUBMED: 15917220.
RA Lee D. K., Kang J. E., Park H. J., Kim M. H., Yim T. H., Kim J. M., Heo M. K., Kim K. Y., Kwon H. J., Hur M. W.
RT FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB.
RL J. Biol. Chem. 280:27783-27791 (2005).
RN [5]; RE0047935.
RX PUBMED: 9765306.
RA Wong C. W., Privalsky M. L.
RT Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.
RL J. Biol. Chem. 273:27695-27702 (1998).
RN [6]; RE0052545.
RX PUBMED: 14769944.
RA Parrado A., Robledo M., Moya-Quiles M. R., Marin L. A., Chomienne C., Padua R. A., Alvarez-Lopez M. R.
RT The promyelocytic leukemia zinc finger protein down-regulates apoptosis and expression of the proapoptotic BID protein in lymphocytes.
RL Proc. Natl. Acad. Sci. USA 101:1898-1903 (2004).
RN [7]; RE0053648.
RX PUBMED: 11719366.
RA Ward J. O., McConnell M. J., Carlile G. W., Pandolfi P. P., Licht J. D., Freedman L. P.
RT The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor.
RL Blood 98:3290-3300 (2001).
RN [8]; RE0063003.
RX PUBMED: 12004059.
RA Lee D. K., Suh D., Edenberg H. J., Hur M. W.
RT POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1.
RL J. Biol. Chem. 277:26761-26768 (2002).
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