TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T00838 XX ID T00838 XX DT 15.10.1992 (created); ewi. DT 16.01.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA T3R-alpha XX SY c-ErbA; c-erbA-1; c-ErbA-alpha; EAR-7; EAR7; NR1A1; Nuclear receptor subfamily 1 group A member 1; T3R; thyroid hormone receptor alpha; TR; TRalpha. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004672 THRA; HGNC: THRA. XX CL C0002; CC (rec); XX SF two splice variants, see T3R-alpha1 T01152, T3R-alpha2 T01153; XX EX placenta,,,adult; high; Northern blot; mRNA (poly-A); [2]. XX IN T25634 ASC-2; mouse, Mus musculus. IN T08300 ER-alpha-L; human, Homo sapiens. IN T04687 NCOR1; human, Homo sapiens. IN T04688 NCOR1; mouse, Mus musculus. IN T00719 NR1B1-isoform1; human, Homo sapiens. IN T00720 RAR-gamma; human, Homo sapiens. IN T00716 RAR; monkey, Cercopithecus aethiops. IN T00717 RAR; mouse, Mus musculus. IN T02746 Rev-ErbAalpha; human, Homo sapiens. IN T01345 RXR-alpha; human, Homo sapiens. IN T01334 RXR-beta; human, Homo sapiens. IN T04807 RXR-gamma; human, Homo sapiens. IN T19335 TIF1a-short; human, Homo sapiens. XX MX M01724 V$T3RALPHA_Q6. MX M00963 V$T3R_Q6. XX BS R65777. BS R65778. BS R02595. BS R00624. BS R03899. BS R29364. BS R03523. XX DR TRANSPATH: MO000025208. DR EMBL: J03239; HSTHRA2A. DR EMBL: M24748; HSTHRA1A. DR EMBL: X04707; HSERBAR. DR EMBL: X55004; HSCERBA7. DR EMBL: X55005; HSCERBAR. DR EMBL: X55066; HSCERBA10. DR EMBL: X55068; HSCERBA9. DR EMBL: X55069; HSCERBA8. DR EMBL: X55070; HSCERBA4. DR EMBL: X55071; HSCERBA5. DR EMBL: X55072; HSCERBA1. DR EMBL: X55073; HSCERBA3. DR EMBL: X55074; HSCERBA2. DR EMBL: Y00479; HSERBT1. DR UniProtKB: P10827; XX RN [1]; RE0001498. RX PUBMED: 1922030. RA Lazar M. A., Berrodin T. J., Harding H. P. RT Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor RL Mol. Cell. Biol. 11:5005-5015 (1991). RN [2]; RE0001829. RX PUBMED: 2879243. RA Weinberger C., Thompson C. C., Ong E. S., Lebo R., Gruol D. J., Evans R. M. RT The c-erb-A gene encodes a thyroid hormone receptor RL Nature 324:641-646 (1986). RN [3]; RE0002102. RX PUBMED: 1850510. RA Laudet V., Begue A., Henry-Duthoit C., Joubel A., Martin P., Stehelin D., Saule S. RT Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene RL Nucleic Acids Res. 19:1105-1112 (1991). RN [4]; RE0002738. RX PUBMED: 2159385. RA Baniahmad A., Steiner C., Koehne A. C., Renkawitz R. RT Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site RL Cell 61:505-514 (1990). RN [5]; RE0017308. RX PUBMED: 9115274. RA Thenot S., Henriquet C., Rochefort H., Cavailles V. RT Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1 RL J. Biol. Chem. 272:12062-12068 (1997). RN [6]; RE0047529. RX PUBMED: 11641275. RA Potter G. B., Beaudoin GM 3. r. d., DeRenzo C. L., Zarach J. M., Chen S. H., Thompson C. C. RT The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. RL Genes Dev. 15:2687-2701 (2001). RN [7]; RE0047600. RX PUBMED: 9717844. RA Lee S. K., Choi H. S., Song M. R., Lee M. O., Lee J. W. RT Estrogen receptor, a common interaction partner for a subset of nuclear receptors. RL Mol. Endocrinol. 12:1184-1192 (1998). RN [8]; RE0047715. RX PUBMED: 11266503. RA Zilliacus J., Holter E., Wakui H., Tazawa H., Treuter E., Gustafsson J. A. RT Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140. RL Mol. Endocrinol. 15:501-511 (2001). RN [9]; RE0047822. RX PUBMED: 10903152. RA Hulkko S. M., Wakui H., Zilliacus J. RT The pro-apoptotic protein death-associated protein 3 (DAP3) interacts with the glucocorticoid receptor and affects the receptor function. RL Biochem. J. 349:885-893 (2000). RN [10]; RE0050597. RX PUBMED: 10681503. RA Caira F., Antonson P., Pelto-Huikko M., Treuter E., Gustafsson J. A. RT Cloning and characterization of RAP250, a novel nuclear receptor coactivator. RL J. Biol. Chem. 275:5308-5317 (2000). RN [11]; RE0050623. RX PUBMED: 9626662. RA Treuter E., Albrektsen T., Johansson L., Leers J., Gustafsson J. A. RT A regulatory role for RIP140 in nuclear receptor activation. RL Mol. Endocrinol. 12:864-881 (1998). RN [12]; RE0054989. RX PUBMED: 15604093. RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M. RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. RL Mol. Cell. Proteomics 4:205-213 (2005). RN [13]; RE0066277. RX PUBMED: 19073200. RA Koury E. J., Pawlyk A. C., Berrodin T. J., Smolenski C. L., Nagpal S., Deecher D. C. RT Characterization of ligands for thyroid receptor subtypes and their interactions with co-regulators. RL Steroids 74:270-276 (2009). XX //