TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02482 XX ID T02482 XX DT 15.06.1998 (created); ewi. DT 03.01.2014 (updated); yre. CO Copyright (C), QIAGEN. XX FA TIF2 XX SY glucocorticoid receptor interacting protein 1; GRIP1; NCoA-2; NCOA2; nuclear receptor coactivator 2; SRC-2; TIF2; transcriptional intermediary factor 2. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G005150 Ncoa2. XX CL C0010; bHLH; XX SF interacts with the hormone-binding domain of nuclear receptors in a ligand-dependent manner [1]; SF NR-box 2 and 3 important for interaction with ERR3 T04644 [3]; XX FF coactivator specifically of nuclear receptor AF-2 function [2]; XX IN T01795 AhR; human, Homo sapiens. IN T00040 AR; human, Homo sapiens. IN T00041 AR; mouse, Mus musculus. IN T01797 arnt; mouse, Mus musculus. IN T15118 CBP; Mammalia. IN T00259 ER-alpha; mouse, Mus musculus. IN T00261 ER-alpha; human, Homo sapiens. IN T09602 ER; Mammalia. IN T04644 ERR3-isoform1; mouse, Mus musculus. IN T04647 ERR3-isoform2; mouse, Mus musculus. IN T01686 GCN5; human, Homo sapiens. IN T00335 GR; mouse, Mus musculus. IN T00511 MR; rat, Rattus norvegicus. IN T01327 NR1B1; mouse, Mus musculus. IN T01331 RXR-alpha; mouse, Mus musculus. IN T08551 SF-1; mouse, Mus musculus. IN T01173 T3R-alpha2; mouse, Mus musculus. IN T00851 T3R-beta1; human, Homo sapiens. IN T00883 VDR; mouse, Mus musculus. IN T05150 ZAC-1b; mouse, Mus musculus. XX DR TRANSPATH: MO000026463. DR UniProtKB: Q61026; NCOA2_MOUSE. XX RN [1]; RE0006903. RX PUBMED: 8643509. RA Hong H., Kohli K., Trivedi A., Johnsson D. L., Stallcup M. R. RT GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors RL Proc. Natl. Acad. Sci. USA 93:4948-4952 (1996). RN [2]; RE0006906. RX PUBMED: 9111344. RA Hong H., Kohli K., Garabedian M. J., Stallcup M. R. RT GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors RL Mol. Cell. Biol. 17:2735-2744 (1997). RN [3]; RE0016449. RX PUBMED: 10428842. RA Hong H., Yang L., Stallcup M. R. RT Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3 RL J. Biol. Chem. 274:22618-22626 (1999). RN [4]; RE0030488. RX PUBMED: 12507421. RA Picard F., Gehin M., Annicotte J., Rocchi S., Champy M. F., O'Malley B. W., Chambon P., Auwerx J. RT SRC-1 and TIF2 control energy balance between white and brown adipose tissues. RL Cell 111:931-41 (2002). RN [5]; RE0035771. RX PUBMED: 10809234. RA Anafi M., Yang Y. F., Barlev N. A., Govindan M. V., Berger S. L., Butt T. R., Walfish P. G. RT GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor. RL Mol. Endocrinol. 14:718-732 (2000). RN [6]; RE0055872. RX PUBMED: 17882261. RA Yue W. W., Hassler M., Roe S. M., Thompson-Vale V., Pearl L. H. RT Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase. RL EMBO J. 26:4402-4412 (2007). RN [7]; RE0065548. RX PUBMED: 19574399. RA Chen J., An B. S., Cheng L., Hammond G. L., Leung P. C. RT Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs. RL Endocrinology 150:4583-4593 (2009). XX //